CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-036823
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 C-type mannose receptor 2 
Protein Synonyms/Alias
  
Gene Name
 MRC2 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
103RTTSCDTKLQGAVCGubiquitination[1]
260ITMGVVCKLPRAEQSubiquitination[2]
331SPTEATEKNILVSDMubiquitination[2, 3]
Reference
 [1] Global identification of modular cullin-RING ligase substrates.
 Emanuele MJ, Elia AE, Xu Q, Thoma CR, Izhar L, Leng Y, Guo A, Chen YN, Rush J, Hsu PW, Yen HC, Elledge SJ.
 Cell. 2011 Oct 14;147(2):459-74. [PMID: 21963094]
 [2] Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization.
 Sarraf SA, Raman M, Guarani-Pereira V, Sowa ME, Huttlin EL, Gygi SP, Harper JW.
 Nature. 2013 Apr 18;496(7445):372-6. [PMID: 23503661]
 [3] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 345 AA 
Protein Sequence
MPTGHLGSPL ALALLPVATN RPAVQWSCTA PQPTSLAAGT IGAARRRPMA SSARRARGSR 60
RYSWVSEEPL NYVGWQDGEP QQPGGCTYVD VDGAWRTTSC DTKLQGAVCG VSSGPPPPRR 120
ISYHGSCPQG LADSAWIPFR EHCYSFHMEL LLGHKEARQR CQRAGGAVLS ILDEMENVFV 180
WEHLQSYEGQ SRGAWLGMNF NPKGGTLVWQ DNTAVNYSNW GPPGLGPSML SHNSCYWIQS 240
NSGLWRPGAC TNITMGVVCK LPRAEQSSFS PSALPENPAA LVVVLMAVLL LLALLTAALI 300
LYRRRQSIER GAFEGARYSR SSSSPTEATE KNILVSDMEM NEQQE 345 
Gene Ontology
 GO:0030246; F:carbohydrate binding; IEA:InterPro. 
Interpro
 IPR001304; C-type_lectin.
 IPR016186; C-type_lectin-like.
 IPR016187; C-type_lectin_fold. 
Pfam
 PF00059; Lectin_C 
SMART
 SM00034; CLECT 
PROSITE
 PS50041; C_TYPE_LECTIN_2 
PRINTS