CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-010248
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Free methionine-R-sulfoxide reductase 
Protein Synonyms/Alias
 fRMsr 
Gene Name
 msrC 
Gene Synonyms/Alias
 yebR; b1832; JW1821 
Created Date
 July 27, 2013 
Organism
 Escherichia coli (strain K12) 
NCBI Taxa ID
 83333 
Lysine Modification
Position
Peptide
Type
References
149QLVAQLEKVLATTDYacetylation[1]
157VLATTDYKKFFASVAacetylation[1]
Reference
 [1] Acetyl-Phosphate Is a Critical Determinant of Lysine Acetylation in E. coli.
 Weinert BT, Iesmantavicius V, Wagner SA, Schölz C, Gummesson B, Beli P, Nyström T, Choudhary C.
 Mol Cell. 2013 Jul 25;51(2):265-72. [PMID: 23830618
Functional Description
 Catalyzes the reversible oxidation-reduction of the R- enantiomer of free methionine sulfoxide to methionine. Specific for free L-methionine-(R)-S-oxide. 
Sequence Annotation
 DOMAIN 49 149 GAF.  
Keyword
 3D-structure; Complete proteome; Oxidoreductase; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 165 AA 
Protein Sequence
MNKTEFYADL NRDFNALMAG ETSFLATLAN TSALLYERLT DINWAGFYLL EDDTLVLGPF 60
QGKIACVRIP VGRGVCGTAV ARNQVQRIED VHVFDGHIAC DAASNSEIVL PLVVKNQIIG 120
VLDIDSTVFG RFTDEDEQGL RQLVAQLEKV LATTDYKKFF ASVAG 165 
Gene Ontology
 GO:0033745; F:L-methionine-(R)-S-oxide reductase activity; IEA:EC.
 GO:0016671; F:oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor; IDA:EcoCyc.
 GO:0006979; P:response to oxidative stress; EXP:EcoCyc. 
Interpro
 IPR003018; GAF.
 IPR000614; UPF0067_CS. 
Pfam
 PF13185; GAF_2 
SMART
 SM00065; GAF 
PROSITE
 PS01320; UPF0067 
PRINTS