CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-038218
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Aminopeptidase B 
Protein Synonyms/Alias
  
Gene Name
 Rnpep 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
162PEQTAGKKKPFVYTQacetylation[1]
359PLNKLRVKIEPGVDPubiquitination[2]
553QEEFQKVKDFLQSQGubiquitination[2]
Reference
 [1] Quantitative acetylome analysis reveals the roles of SIRT1 in regulating diverse substrates and cellular pathways.
 Chen Y, Zhao W, Yang JS, Cheng Z, Luo H, Lu Z, Tan M, Gu W, Zhao Y.
 Mol Cell Proteomics. 2012 Oct;11(10):1048-62. [PMID: 22826441]
 [2] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 611 AA 
Protein Sequence
MESGGPGNYS AAARRPLHSA QAVDVASASS FRAFEILHLH LDLRAEFGPP GPGPGSRGLS 60
GTATLELRCL LPEGASELRL DSHSCLEVTA ATLRRGQPGD QQAPAEPVPF HTQPFSHYGQ 120
ALCVAFRQPC GAADRFELEL TYRVGEGPGV CWLAPEQTAG KKKPFVYTQG QAVLNRAFFP 180
CFDTPAVKCT YSALIEVPDG FTAVMSADTW EKRGPNKFFF QMSHPIPSYL IALAIGDLAS 240
AEVGPRYDLL FMPPSFPFGG MENPCLTFVT PCLLAGDRSL ADVIIHEISH SWFGNLVTNA 300
NWGEFWLNEG FTMYAQRRIS TILFGAAYTC LEAATGRALL RQHMNVSGEE NPLNKLRVKI 360
EPGVDPDDTY NETPYEKGYC FVSYLAHLVG DQDQFDKFLK AYVDEFKFQS ILAEDFLEFY 420
LEYFPELKKK GVDSIPGFEF DRWLNTPGWP PYLPDLSPGD SLMKPAEELA ELWVTSEPDM 480
QAIEAVAIST WKTYQLVYFL DKILQKSPLP PGNVKKLGET YPKISNAQNA ELRLRWGQII 540
LKNDYQEEFQ KVKDFLQSQG KQKYTLPLYH AMMGGSEMAR TLAKDTFAAT ASQLHSNVVN 600
YVQQILAPKD S 611 
Gene Ontology
 GO:0005615; C:extracellular space; IEA:InterPro.
 GO:0004177; F:aminopeptidase activity; IEA:InterPro.
 GO:0008237; F:metallopeptidase activity; IEA:InterPro.
 GO:0008270; F:zinc ion binding; IEA:InterPro.
 GO:0019370; P:leukotriene biosynthetic process; IEA:InterPro.
 GO:0006508; P:proteolysis; IEA:InterPro. 
Interpro
 IPR016024; ARM-type_fold.
 IPR015571; Pept_M1_aminopeptidase-B.
 IPR001930; Peptidase_M1.
 IPR015211; Peptidase_M1_C.
 IPR014782; Peptidase_M1_N. 
Pfam
 PF09127; Leuk-A4-hydro_C
 PF01433; Peptidase_M1 
SMART
  
PROSITE
  
PRINTS
 PR00756; ALADIPTASE.