CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-038645
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 E3 ubiquitin-protein ligase makorin-1 
Protein Synonyms/Alias
  
Gene Name
 Mkrn1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
49YEHSKPLKQEEVTATubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Metal-binding; Reference proteome; Zinc; Zinc-finger. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 417 AA 
Protein Sequence
MHGVCKEGDN CRYSHDLSDS PYGVVCKYFQ RGYCVYGDRC RYEHSKPLKQ EEVTATDLSA 60
KPSLAASSSL SSGVGSLAEM NSGEAESRNP SFPTVGAGSE DWVNAIEFVP GQPYCGRTAP 120
SCTEVPPQGS VTKEESEKEP TTVETKKQLC PYAAVGECRY GENCVYLHGD SCDMCGLQVL 180
HPVDAAQRSQ HIKSCIEAHE KDMELSFAVQ RSKDMVCGIC MEVVYEKANP SERRFGILSN 240
CNHTYCLKCI RKWRSAKQFE SKIIKSCPEC RITSNFVIPS ENWVEEKEEK QKLIQKYKEA 300
MSNKACRYFD EGRGSCPFGG NCFYKHAYPD GRREEPQRQK VGTSSRYRAQ RRSHFWELIE 360
ERENNPFDND EEEVVTFELG EMLLMLLAAG GDDELTDSED EWDLFHDELE DFYDLDL 417 
Gene Ontology
 GO:0003682; F:chromatin binding; IDA:MGI.
 GO:0003676; F:nucleic acid binding; IEA:InterPro.
 GO:0008270; F:zinc ion binding; IEA:InterPro. 
Interpro
 IPR026290; Makorin-related.
 IPR000571; Znf_CCCH.
 IPR001841; Znf_RING.
 IPR013083; Znf_RING/FYVE/PHD.
 IPR017907; Znf_RING_CS. 
Pfam
 PF00642; zf-CCCH
 PF13639; zf-RING_2 
SMART
 SM00184; RING
 SM00356; ZnF_C3H1 
PROSITE
 PS50103; ZF_C3H1
 PS00518; ZF_RING_1
 PS50089; ZF_RING_2 
PRINTS