UniProt Accession

 TRML_MYCPN; P75257 

Genbank Protein ID

 U00089 

Genbank Nucleotide ID

 AAB95969.1 

Protein Name

 Putative tRNA (cytidine(34)-2'-O)-methyltransferase 

Protein Synonyms/Alias

 tRNA (cytidine/uridine-2'-O-)-methyltransferase 

Gene Name

 MPN_521; G12_orf166b, MP321 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Mycoplasma pneumoniae (strain ATCC 29342 / M129) 

NCBI Taxa ID

 272634 

Lysine Modification

Position	Peptide	Type	References
37	KANLHLIKPYGFFLN	acetylation	[1]

Reference

 [1] Cross-talk between phosphorylation and lysine acetylation in a genome-reduced bacterium.
 van Noort V, Seebacher J, Bader S, Mohammed S, Vonkova I, Betts MJ, Kühner S, Kumar R, Maier T, O'Flaherty M, Rybin V, Schmeisky A, Yus E, Stülke J, Serrano L, Russell RB, Heck AJ, Bork P, Gavin AC.
 Mol Syst Biol. 2012 Feb 28;8:571. [PMID: 22373819] 

Functional Description

 Could methylate the ribose at the nucleotide 34 wobble position in tRNA (By similarity). 

Sequence Annotation

 BINDING 83 83 S-adenosyl-L-methionine; via carbonyl
 BINDING 109 109 S-adenosyl-L-methionine; via amide
 BINDING 130 130 S-adenosyl-L-methionine; via amide
 BINDING 138 138 S-adenosyl-L-methionine (By similarity).  

Keyword

 Complete proteome; Cytoplasm; Methyltransferase; Reference proteome; S-adenosyl-L-methionine; Transferase; tRNA processing. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 166 AA 

Protein Sequence

Gene Ontology

 GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
 GO:0003723; F:RNA binding; IEA:InterPro.
 GO:0008757; F:S-adenosylmethionine-dependent methyltransferase activity; IEA:HAMAP.
 GO:0008175; F:tRNA methyltransferase activity; IEA:HAMAP. 

Interpro

 IPR001537; SpoU_MeTrfase.
 IPR016914; tRNA_cyt/urid_MeTfrase. 

Pfam

 PF00588; SpoU_methylase 

SMART

  

PROSITE

  

PRINTS