| Tag | Content |
|---|
| CPLM ID | CPLM-007063 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Inositolphosphotransferase 1 |
Protein Synonyms/Alias | Mannosyl diphosphorylinositol ceramide synthase |
Gene Name | IPT1 |
Gene Synonyms/Alias | SYR4; YDR072C; D4405; YD8554.05C |
Created Date | July 27, 2013 |
Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) |
NCBI Taxa ID | 559292 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 409 | INSNGNKKPLQFVHL | ubiquitination | [1] | | 499 | IHIRLGDKVDTRNEA | ubiquitination | [1] |
|
Reference | [1] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation. Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, Villén J. Nat Methods. 2013 Jul;10(7):676-82. [ PMID: 23749301] |
Functional Description | Catalyzes the addition of a phosphorylinositol group onto mannosyl phosphorylinositol ceramide to form mannosyl diphosphorylinositol ceramide. |
Sequence Annotation | |
Keyword | Complete proteome; Membrane; Reference proteome; Transferase; Transmembrane; Transmembrane helix. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 527 AA |
Protein Sequence | MNVIFSLASF VKNMYNASLN QRNLISLPFN FMLNFAPVFI WLSIFKRAGL IPIRLRPDIH 60
SKFAFFADQF LFGDYWHELT VQLPDNTSKL FFWSFISSSA FLLVFLICIP FAIWYYIYYI 120
KHVNYNLLEW FANIFHYPCK RKQRPIQKRF RTIFIPFALP LFTFVILNID HFFAYQSDAN 180
FTKTKDLLAW FSYVILHLTA PILTAVYLYV FQPPGTLKCF SFALGLQNIA GVLTHLLVPM 240
ASPWFTHLYG IDDTEHVNYT QEGFAAGLIR VDSHLGTHLN TKGFHMSPIV FGAVPSLHSA 300
IAFQCFLFLV SRSTSLKHRF SNAGGFTMHN NDSSTFKLSE EDSEDEGDNS IPPTIGPNDL 360
EMEPLGTVEP VDISNERSSS PSSSFTVSSN ERSTGGGDGS IINSNGNKKP LQFVHLYDED 420
TNFTNKWIFK IVNDGFIPKF WAILYIILQW WATMYLDHHY RFDLFVGVLY AMTSFIIINW 480
FVLQPKVLKK WIHIRLGDKV DTRNEARTFG MRVFCGTKME WFFDPLA 527 |
Gene Ontology | GO:0016021; C:integral to membrane; ISM:SGD. GO:0016772; F:transferase activity, transferring phosphorus-containing groups; IDA:SGD. GO:0006676; P:mannosyl diphosphorylinositol ceramide metabolic process; IDA:SGD. GO:0030148; P:sphingolipid biosynthetic process; IGI:SGD. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |