UniProt Accession

 H32_ONCMY; P84234; P02295; P02297; P16105; P17269; P17320 

Genbank Protein ID

 X01064 

Genbank Nucleotide ID

 CAA25529.1 

Protein Name

 Histone H3.2 

Protein Synonyms/Alias

  

Gene Name

  

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri) 

NCBI Taxa ID

 8022 

Lysine Modification

Position	Peptide	Type	References
10	RTKQTARKSTGGKAP	acetylation	[1]
15	ARKSTGGKAPRKQLA	acetylation	[1]
19	TGGKAPRKQLATKAA	acetylation	[1]
24	PRKQLATKAARKSAP	acetylation	[1]

Reference

 [1] Multiacetylated forms of H4 are found in a putative transcriptionally competent chromatin fraction from trout testis.
 Levy-Wilson B, Watson DC, Dixon GH.
 Nucleic Acids Res. 1979 Jan;6(1):259-74. [PMID: 424292] 

Functional Description

 Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. 

Sequence Annotation

 MOD_RES 3 3 Asymmetric dimethylarginine; by PRMT6 (By
 MOD_RES 4 4 Phosphothreonine; by GSG2 (By
 MOD_RES 5 5 Allysine; alternate (By similarity).
 MOD_RES 5 5 N6,N6,N6-trimethyllysine; alternate (By
 MOD_RES 5 5 N6,N6-dimethyllysine; alternate (By
 MOD_RES 5 5 N6-acetyllysine; alternate (By
 MOD_RES 5 5 N6-methyllysine; alternate (By
 MOD_RES 7 7 Phosphothreonine; by PKC (By similarity).
 MOD_RES 10 10 N6-acetyllysine; alternate.
 MOD_RES 10 10 N6-methylated lysine; alternate (By
 MOD_RES 11 11 Phosphoserine; by AURKB, AURKC, RPS6KA3,
 MOD_RES 12 12 Phosphothreonine; by PKC (By similarity).
 MOD_RES 15 15 N6-acetyllysine.
 MOD_RES 18 18 Asymmetric dimethylarginine (By
 MOD_RES 19 19 N6-acetyllysine; alternate.
 MOD_RES 19 19 N6-methylated lysine; alternate (By
 MOD_RES 24 24 N6-acetyllysine.
 MOD_RES 28 28 N6-acetyllysine; alternate (By
 MOD_RES 28 28 N6-methylated lysine; alternate (By
 MOD_RES 29 29 Phosphoserine; by AURKB, AURKC and
 MOD_RES 37 37 N6-acetyllysine; alternate (By
 MOD_RES 37 37 N6-methylated lysine; alternate (By
 MOD_RES 42 42 Phosphotyrosine (By similarity).
 MOD_RES 58 58 Phosphoserine (By similarity).
 MOD_RES 65 65 N6-methylated lysine (By similarity).
 MOD_RES 80 80 N6-methylated lysine (By similarity).
 MOD_RES 81 81 Phosphothreonine (By similarity).
 MOD_RES 123 123 N6-methylated lysine (By similarity).  

Keyword

 Acetylation; Chromosome; Direct protein sequencing; DNA-binding; Methylation; Nucleosome core; Nucleus; Phosphoprotein; Ubl conjugation. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 136 AA 

Protein Sequence

Gene Ontology

 GO:0000786; C:nucleosome; IEA:UniProtKB-KW.
 GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
 GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
 GO:0006334; P:nucleosome assembly; IEA:InterPro. 

Interpro

 IPR009072; Histone-fold.
 IPR007125; Histone_core_D.
 IPR000164; Histone_H3. 

Pfam

 PF00125; Histone 

SMART

 SM00428; H3 

PROSITE

 PS00322; HISTONE_H3_1
 PS00959; HISTONE_H3_2 

PRINTS

 PR00622; HISTONEH3.