CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-001435
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Syntaxin-8 
Protein Synonyms/Alias
 Syntaxin-like protein 3I35 
Gene Name
 Stx8 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
59KVKIDLLKDLLLRAVubiquitination[1]
98RLLLASFKNEGAEPDubiquitination[1]
146EIRQQQQKIIQEQDAubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
 Vesicle trafficking protein that functions in the early secretory pathway, possibly by mediating retrograde transport from cis-Golgi membranes to the ER (By similarity). 
Sequence Annotation
 DOMAIN 145 207 t-SNARE coiled-coil homology.  
Keyword
 Coiled coil; Complete proteome; Membrane; Reference proteome; Transmembrane; Transmembrane helix; Transport; Ubl conjugation. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 236 AA 
Protein Sequence
MAPDPWFSTY DSTCQIAQEI AEKIQERNQC ERRGEKTPKL TLTIRTLLKN LKVKIDLLKD 60
LLLRAVSTRQ ITQLEGDRRQ NLLDDLVTRE RLLLASFKNE GAEPDLIRSS LMSEEAKRGT 120
PNPWLCEEPE ETRGLGFDEI RQQQQKIIQE QDAGLDALSS IISRQKQMGQ EIGNELDEQN 180
EIIDDLANLV ENTDEKLRTE ARRVTLVDRK STSCGMIMVI LLLLVAIVVV AVWPTN 236 
Gene Ontology
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0031902; C:late endosome membrane; IEA:Compara.
 GO:0005765; C:lysosomal membrane; IEA:Compara.
 GO:0031201; C:SNARE complex; IEA:Compara.
 GO:0008333; P:endosome to lysosome transport; IEA:Compara.
 GO:0006906; P:vesicle fusion; IEA:Compara. 
Interpro
 IPR015640; Syntax_8.
 IPR000727; T_SNARE_dom. 
Pfam
 PF05739; SNARE 
SMART
 SM00397; t_SNARE 
PROSITE
 PS00914; SYNTAXIN
 PS50192; T_SNARE 
PRINTS