CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-024743
UniProt Accession
Genbank Protein ID
  
Genbank Nucleotide ID
  
Protein Name
 Probable G-protein coupled receptor 158 
Protein Synonyms/Alias
  
Gene Name
 Gpr158 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
720DIRDELKKLYAQLEIubiquitination[1]
732LEIYKRKKMITNNPHubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
 Orphan receptor. 
Sequence Annotation
 MOD_RES 904 904 Phosphoserine (By similarity).
 CARBOHYD 98 98 N-linked (GlcNAc...) (Potential).
 CARBOHYD 143 143 N-linked (GlcNAc...) (Potential).
 CARBOHYD 215 215 N-linked (GlcNAc...) (Potential).
 CARBOHYD 274 274 N-linked (GlcNAc...) (Potential).
 CARBOHYD 333 333 N-linked (GlcNAc...) (Potential).
 CROSSLNK 774 774 Glycyl lysine isopeptide (Lys-Gly)  
Keyword
 Cell membrane; Complete proteome; G-protein coupled receptor; Glycoprotein; Isopeptide bond; Membrane; Phosphoprotein; Receptor; Reference proteome; Signal; Transducer; Transmembrane; Transmembrane helix; Ubl conjugation. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1202 AA 
Protein Sequence
MGAMAYSLLL CLLLAHLGLG EVGASLDPSE RPDSSRERTS RGKQHGQQLP RASAPDPSIP 60
WSRSTDGTIL AQKLAEEVPM DVASYLYTGD FHQLKRANCS GRYELAGLPG KSPSLASSHP 120
SLHGALDTLT HATNFLNMML QSNKSREQTV QDDLQWYQAL VRSLLEGEPS ISRAAITFST 180
ESLSTPAPQV FLQATREESR ILLQDLSSSA HHLANATLET EWFHGLRRKW RPHLHRRGSN 240
QGPRGLGHSW RRRDGLGGDR SHVKWSPPFL ECENGSYKPG WLVTLSAAFY GLQPNLVPEF 300
RGVMKVDINL QKVDIDQCSS DGWFSGTHKC HLNNSECMPI KGLGFVLGAY QCVCKAGFYH 360
PRVFSVNNFQ RRGPDHHFSG STKDVSEEAH VCLPCREGCP FCADDRPCFV QEDKYLRLAI 420
ISFQALCMLL DFVSMLVVYH FRKAKSIRAS GLILLETILF GSLLLYFPVV ILYFEPSTFR 480
CILLRWVRLL GFATVYGTVT LKLHRVLKVF LSRTAQRIPY MTGGRVMRML AVIVLVVFWF 540
LVGWTSSMCQ NLERDILLVG QGQTSDNLTF NMCLIDRWDY MTAVAEFLFL LWGIYLCYAV 600
RTVPSAFHEP RYMAVAVHNE LIITAIFHTI RFVLASRLQP DWMLMLYFAH THLTVTVTIG 660
LLLIPKFSHS SNNPRDDIAT EAYEDELDMG RSGSYLNSSI NSAWSEHSLD PEDIRDELKK 720
LYAQLEIYKR KKMITNNPHL QKKRCSKKGL GRSIMRRITE IPETVSRQCS KEDKEGTDHS 780
AAKGTGLVRK NPTESSGNTG RPKEESLKNR VFSLKKSHST YDHVRDQTDE SSSLPTESQE 840
EEVTENSTLE SLSSKKLTQK VKEDSEAEST ESVPLVCKSA SAHNLSSEKK PGHPRTSMLQ 900
KSLSVIASAK EKTLGLAGKT QTLVMEDRAK SQKPQPKDRE TNRKYSNSDN TETNPNSNHT 960
EELRKPQKSG IMKQQRVNLP TANPDASSST TQIKDNFDIG EVCPWEVYDL TPGPVPSEPK 1020
AQKHVSIAAS EVEQNPASFS KEKSHHKPKA AEGLYQANHK SIDKTEVCPW ESHGQSPLED 1080
ENRLISKTPV LPGRAREENG SQLYTTNMCA GQYEELPPKA VASKVENENL NQMGDQEKQT 1140
SSSVDIIPGS CISSNNSPQP LTSRAEVCPW EFEPLEQPNA ERIVALPASS ALSASKIPGP 1200
RK 1202 
Gene Ontology
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
 GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
 GO:0072659; P:protein localization to plasma membrane; IEA:Compara.
 GO:0008277; P:regulation of G-protein coupled receptor protein signaling pathway; IEA:Compara. 
Interpro
 IPR017978; GPCR_3_C. 
Pfam
 PF00003; 7tm_3 
SMART
  
PROSITE
 PS50259; G_PROTEIN_RECEP_F3_4 
PRINTS