CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-040308
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Acyl-CoA-binding protein 
Protein Synonyms/Alias
  
Gene Name
 Dbi 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
28DKAAEEVKRLKTQPTacetylation[1]
31AEEVKRLKTQPTDEEacetylation[2, 3]
31AEEVKRLKTQPTDEEsuccinylation[3]
31AEEVKRLKTQPTDEEubiquitination[4]
47LFIYSHFKQATVGDVubiquitination[4]
Reference
 [1] Quantification of mitochondrial acetylation dynamics highlights prominent sites of metabolic regulation.
 Still AJ, Floyd BJ, Hebert AS, Bingman CA, Carson JJ, Gunderson DR, Dolan BK, Grimsrud PA, Dittenhafer-Reed KE, Stapleton DS, Keller MP, Westphall MS, Denu JM, Attie AD, Coon JJ, Pagliarini DJ.
 J Biol Chem. 2013 Jul 17;. [PMID: 23864654]
 [2] Quantitative acetylome analysis reveals the roles of SIRT1 in regulating diverse substrates and cellular pathways.
 Chen Y, Zhao W, Yang JS, Cheng Z, Luo H, Lu Z, Tan M, Gu W, Zhao Y.
 Mol Cell Proteomics. 2012 Oct;11(10):1048-62. [PMID: 22826441]
 [3] SIRT5-Mediated Lysine Desuccinylation Impacts Diverse Metabolic Pathways.
 Park J, Chen Y, Tishkoff DX, Peng C, Tan M, Dai L, Xie Z, Zhang Y, Zwaans BM, Skinner ME, Lombard DB, Zhao Y.
 Mol Cell. 2013 Jun 27;50(6):919-30. [PMID: 23806337]
 [4] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 101 AA 
Protein Sequence
XNYSQHLTQC CNCLSGQAEF DKAAEEVKRL KTQPTDEEML FIYSHFKQAT VGDVNTDRPG 60
LLDLKGKAKW DSWNKLKGTS KESAMKTYVE KVDELKKKYG I 101 
Gene Ontology
 GO:0005739; C:mitochondrion; IDA:MGI.
 GO:0000062; F:fatty-acyl-CoA binding; IEA:InterPro.
 GO:0001942; P:hair follicle development; IMP:MGI.
 GO:0043588; P:skin development; IMP:MGI.
 GO:0006641; P:triglyceride metabolic process; IMP:MGI. 
Interpro
 IPR022408; Acyl-CoA-binding_prot_CS.
 IPR000582; Acyl-CoA-binding_protein.
 IPR014352; FERM/acyl-CoA-bd_prot_3-hlx. 
Pfam
 PF00887; ACBP 
SMART
  
PROSITE
 PS00880; ACB_1
 PS51228; ACB_2 
PRINTS
 PR00689; ACOABINDINGP.