CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-026458
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Diphosphomevalonate decarboxylase 
Protein Synonyms/Alias
 Mevalonate (Diphospho) decarboxylase 
Gene Name
 Mvd 
Gene Synonyms/Alias
 rCG_51261 
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
27AVIKYWGKRDEALILacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 401 AA 
Protein Sequence
MASEKPQDLM VTCTAPVNIA VIKYWGKRDE ALILPINSSL SVTLHQDQLK TTTTAAISKD 60
FTEDRIWLNG REEDVGQPRL QACLREIRRL ARKRRSTGDG DALPLSLGYK VHVASVNNFP 120
TAAGLASSAA GYACLAYTLA RVYGVEGDLS EVARRGSGSA CRSLYGGFVE WQMGEQADGK 180
DSIARQIAPE WHWPQLRVLI LVVSAEKKPT GSTVGMQTSV ATSTLLKFRA ESIVPERMKE 240
MTRCIQEQDF QAFAQLTMKD SNQFHATCLD TFPPISYLND TSRRIIQLVH RFNAHHGQTK 300
VAYTFDAGPN AVIFTLEDTV AEFVAAVRHS FPPAANGDKF LKGLQVAPVL LSDELKTSLA 360
TEPSPGGVQY IIATQVGPGP QVLDDPHHHL LGPDGLPQRD L 401 
Gene Ontology
 GO:0005829; C:cytosol; IEA:Compara.
 GO:0005524; F:ATP binding; IEA:InterPro.
 GO:0004163; F:diphosphomevalonate decarboxylase activity; IEA:Compara.
 GO:0008299; P:isoprenoid biosynthetic process; IEA:Compara.
 GO:0008284; P:positive regulation of cell proliferation; IEA:Compara. 
Interpro
 IPR006204; GHMP_kinase_N_dom.
 IPR005935; Mev_diP_decarb.
 IPR020568; Ribosomal_S5_D2-typ_fold.
 IPR014721; Ribosomal_S5_D2-typ_fold_subgr. 
Pfam
 PF00288; GHMP_kinases_N 
SMART
  
PROSITE
  
PRINTS