| Tag | Content |
|---|
| CPLM ID | CPLM-009174 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Ankyrin repeat and SAM domain-containing protein 1A |
Protein Synonyms/Alias | Odin |
Gene Name | Anks1a |
Gene Synonyms/Alias | Anks1; Kiaa0229; Odin |
Created Date | July 27, 2013 |
Organism | Mus musculus (Mouse) |
NCBI Taxa ID | 10090 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 1162 | SKRSLSTKYETTIF* | ubiquitination | [1] |
|
Reference | [1] Synaptic protein ubiquitination in rat brain revealed by antibody-based ubiquitome analysis. Na CH, Jones DR, Yang Y, Wang X, Xu Y, Peng J. J Proteome Res. 2012 Sep 7;11(9):4722-32. [ PMID: 22871113] |
Functional Description | Regulator of different signaling pathways. Regulates EPHA8 receptor tyrosine kinase signaling to control cell migration and neurite retraction. |
Sequence Annotation | REPEAT 75 104 ANK 1.
REPEAT 108 137 ANK 2.
REPEAT 165 194 ANK 3.
REPEAT 198 227 ANK 4.
REPEAT 231 260 ANK 5.
REPEAT 263 292 ANK 6.
DOMAIN 712 778 SAM 1.
DOMAIN 786 853 SAM 2.
DOMAIN 952 1107 PID.
MOD_RES 2 2 N-acetylglycine (By similarity).
MOD_RES 335 335 Phosphothreonine (By similarity).
MOD_RES 638 638 Phosphoserine (By similarity).
MOD_RES 640 640 Phosphoserine.
MOD_RES 642 642 Phosphoserine.
MOD_RES 644 644 Phosphoserine.
MOD_RES 663 663 Phosphoserine.
MOD_RES 677 677 Phosphoserine (By similarity).
MOD_RES 679 679 Phosphoserine.
MOD_RES 682 682 Phosphoserine.
MOD_RES 903 903 Phosphoserine. |
Keyword | Acetylation; Alternative splicing; ANK repeat; Cell projection; Complete proteome; Cytoplasm; Phosphoprotein; Reference proteome; Repeat. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 1150 AA |
Protein Sequence | MGKEQELLEA ARTGHLPAVE KLLSGKRLSS GFGGGGGGSG SGGGSGGGGL GSSSHPLSSL 60
LSMWRGPNVN CVDSTGYTPL HHAALNGHRD VVEVLLRNDA LTNVADSKGC YPLHLAAWKG 120
DAQIVRLLIQ QGPSHTRVNE QNNDNETALH CAAQYGHTEV VKALLEELTD PTMRNNKFET 180
PLDLAALYGR LEVVKLLLGA HPNLLSCSTR KHTPLHLAAR NGHKAVVQVL LDAGMDSNYQ 240
TEMGSALHEA ALFGKTDVVQ ILLAAGIDVN IKDNRGLTAL DTVRDLPSQK SQQIAALIED 300
HMTGKRSVKE VDRTSTAQLP LLSNTDAIAP MSQGSMEKTV TELILHFDTH ADEEGPYEAL 360
YNAVSCHSLD STASGRSSDR DSMNKEAEAT GTRAAGVRPR ERPPPPAKPP PDEEEEERVD 420
KKYFPLAASE GLAVRPRIQS SAPQEEEEHP YELLLTAETK KLGTTDGRTE DHRQSGSGRS 480
QDSVEGQDGQ VPEQFSGLLH GSSPVCEVGQ DPFQLLTAPS QSHPESSQQD ACHEASMQLE 540
EPGVQGTEPP QPGVPDQSKR VGLPAGLTAL ASRTYLDALT HTVPLRPAGA EEEDQSGPRS 600
RAPPTSKPKA ELKLSRSLSK SDSDLLTCSP TEDATMGSRS ESLSNCSIGK KRLEKSPSFA 660
SEWDEIEKIM SSIGEGIDFS QEQQKISGSR TLEQSVGEWL ESIGLQQYES KLLLNGFDDV 720
RFLGSNVMEE QDLREIGISD PQHRRKLLQA ARSLPKVKAL GYDGVSPTSV PSWLDSLGLQ 780
DYVHSFLSSG YSSIDTVKNL WELELVNVLK VHLLGHRKRI IASLADRPYE EPPQKPPRFS 840
QLRCQDLISQ TSSPLSQNDS CTGRSADLLL PSADTSRRRH DSLPDPGTAS RADRFRVQEE 900
PSETKLTLRP PSLAAPYAPV QSWQHQPEKL IFESCGYEAN YLGSMLIKDL RGTESTQDAC 960
AKMRKSTEHM KKIPTIILSI TYKGVKFIDA SNKNVIAEHE IRNISCAAQD PEDLCTFAYI 1020
TKDLQTSHHY CHVFSTVDVN LTYEIILTLG QAFEVAYQLA LQAQKSRTMA ASAASMIETK 1080
SSKPVPKPRV GMRKSAVPVP PDSRCCHCHT CTTHRPSYLP LPSVSPGVKL EPPDSDQEAP 1140
SHASVSWIVD PKPDSKRSLS TKYETTIF 1168 |
Gene Ontology | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. GO:0043005; C:neuron projection; IDA:UniProtKB. GO:0005634; C:nucleus; IEA:Compara. GO:0048013; P:ephrin receptor signaling pathway; IMP:UniProtKB. GO:0016322; P:neuron remodeling; IMP:UniProtKB. GO:0006929; P:substrate-dependent cell migration; IDA:UniProtKB. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |