CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-020065
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Coiled-coil domain-containing protein 77 
Protein Synonyms/Alias
  
Gene Name
 CCDC77 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
65LLEYYQKKMAECEAEubiquitination[1]
78AENEDLLKKLELYKEubiquitination[1]
165GEVTYFCKEPPHKVTubiquitination[1]
193QSESSAFKADPKISKubiquitination[1, 2]
301SENQNKEKSWMLEKDubiquitination[1]
330KKEDKIGKVLPVMHEubiquitination[1]
352YIKSLKDKLVQEKKLubiquitination[1]
440DLEQMLYKATVNARAubiquitination[1]
477ELKNLKSKVFGLENEubiquitination[1, 3]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition.
 Udeshi ND, Mani DR, Eisenhaure T, Mertins P, Jaffe JD, Clauser KR, Hacohen N, Carr SA.
 Mol Cell Proteomics. 2012 May;11(5):148-59. [PMID: 22505724]
 [3] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302
Functional Description
  
Sequence Annotation
  
Keyword
 Alternative splicing; Coiled coil; Complete proteome; Polymorphism; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 488 AA 
Protein Sequence
MNFTPTHTPV CRKRTVVSKR GVAVSGPTKR RGMADSLEST PLPSPEDRLA KLHPSKELLE 60
YYQKKMAECE AENEDLLKKL ELYKEACEGQ HKLECDLQQR EEEIAELQKA LSDMQVCLFQ 120
EREHVLRLYS ENDRLRIREL EDKKKIQNLL ALVGTDAGEV TYFCKEPPHK VTILQKTIQA 180
VGECEQSESS AFKADPKISK RRPSRERKES SEHYQRDIQT LILQVEALQA QLGEQTKLSR 240
EQIEGLIEDR RIHLEEIQVQ HQRNQNKIKE LTKNLHHTQE LLYESTKDFL QLRSENQNKE 300
KSWMLEKDNL MSKIKQYRVQ CKKKEDKIGK VLPVMHESHH AQSEYIKSLK DKLVQEKKLS 360
NMYQEQCISL EEELARIREE EGMRREIFKD RTNKMGKRLQ IMTKRYEALE RRRILEVEGF 420
KTDIKVLRQK LKDLEQMLYK ATVNARANQD LALLCEVRDS NRRAHKIQGE LKNLKSKVFG 480
LENELRLC 488 
Gene Ontology
 GO:0005813; C:centrosome; IDA:UniProtKB. 
Interpro
  
Pfam
  
SMART
  
PROSITE
  
PRINTS