CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-005700
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Carbonic anhydrase-related protein 
Protein Synonyms/Alias
 CARP; Carbonic anhydrase VIII; CA-VIII 
Gene Name
 Ca8 
Gene Synonyms/Alias
 Cals; Cals1; Car8; Carp 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
193ILQDIQYKGKSKTIPubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023
Functional Description
 Does not have a carbonic anhydrase catalytic activity. 
Sequence Annotation
 METAL 119 119 Zinc (Potential).
 METAL 142 142 Zinc (Potential).  
Keyword
 Complete proteome; Direct protein sequencing; Metal-binding; Reference proteome; Zinc. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 291 AA 
Protein Sequence
MADLSFIEDA VAFPEKEEDE EEEEEEGVEW GYEEGVEWGL VFPDANGEYQ SPINLNSREA 60
RYDPSLLDVR LSPNYVVCRD CEVTNDGHTI QVILKSKSVL SGGPLPQGQE FELYEVRFHW 120
GRENQRGSEH TVNFKAFPME LHLIHWNSTL FGSIDEAVGK PHGIAIIALF VQIGKEHVGL 180
KAVTEILQDI QYKGKSKTIP CFNPNTLLPD PLLRDYWVYE GSLTIPPCSE GVTWILFRYP 240
LTISQMQIEE FRRLRTHVKG AELVEGCDGI LGDNFRPTQP LSDRVIRAAF Q 291 
Gene Ontology
 GO:0005737; C:cytoplasm; IDA:MGI.
 GO:0004089; F:carbonate dehydratase activity; IEA:InterPro.
 GO:0008270; F:zinc ion binding; IEA:InterPro.
 GO:0006730; P:one-carbon metabolic process; IEA:InterPro.
 GO:0048015; P:phosphatidylinositol-mediated signaling; IDA:MGI. 
Interpro
 IPR001148; Carbonic_anhydrase_a.
 IPR023561; Carbonic_anhydrase_a-class.
 IPR018338; Carbonic_anhydrase_a-class_CS.
 IPR018434; Carbonic_anhydrase_RP_CA8. 
Pfam
 PF00194; Carb_anhydrase 
SMART
 SM01057; Carb_anhydrase 
PROSITE
 PS00162; ALPHA_CA_1
 PS51144; ALPHA_CA_2 
PRINTS