UniProt Accession

 Q6VYI4_MOUSE; Q6VYI4 

Genbank Protein ID

 AL606969; AY319516 

Genbank Nucleotide ID

 AAP92691.1 

Protein Name

 TAR DNA-binding protein 43 

Protein Synonyms/Alias

 TARDBP S9 

Gene Name

 Tardbp 

Gene Synonyms/Alias

 TARDBP 

Created Date

 July 27, 2013 

Organism

 Mus musculus (Mouse) 

NCBI Taxa ID

 10090 

Lysine Modification

Position	Peptide	Type	References
84	YPKDNKRKMDETDAS	acetylation	[1]
95	TDASSAVKVKRAVQK	ubiquitination	[2]
102	KVKRAVQKTSDLIVL	ubiquitination	[2]
114	IVLGLPWKTTEQDLK	ubiquitination	[2]
160	TEYETQVKVMSQRHM	ubiquitination	[2]
176	DGRWCDCKLPNSKQS	acetylation	[3]
181	DCKLPNSKQSPDEPL	ubiquitination	[2]

Reference

 [1] SIRT5-Mediated Lysine Desuccinylation Impacts Diverse Metabolic Pathways.
 Park J, Chen Y, Tishkoff DX, Peng C, Tan M, Dai L, Xie Z, Zhang Y, Zwaans BM, Skinner ME, Lombard DB, Zhao Y.
 Mol Cell. 2013 Jun 27;50(6):919-30. [PMID: 23806337]
 [2] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023]
 [3] Quantitative acetylome analysis reveals the roles of SIRT1 in regulating diverse substrates and cellular pathways.
 Chen Y, Zhao W, Yang JS, Cheng Z, Luo H, Lu Z, Tan M, Gu W, Zhao Y.
 Mol Cell Proteomics. 2012 Oct;11(10):1048-62. [PMID: 22826441] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 304 AA 

Protein Sequence

Gene Ontology

 GO:0003676; F:nucleic acid binding; IEA:InterPro.
 GO:0000166; F:nucleotide binding; IEA:InterPro. 

Interpro

 IPR012677; Nucleotide-bd_a/b_plait.
 IPR000504; RRM_dom. 

Pfam

 PF00076; RRM_1 

SMART

 SM00360; RRM 

PROSITE

 PS50102; RRM 

PRINTS