Tag | Content |
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CPLM ID | CPLM-015882 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | PHD finger protein rhinoceros |
Protein Synonyms/Alias | |
Gene Name | rno |
Gene Synonyms/Alias | CG7036 |
Created Date | July 27, 2013 |
Organism | Drosophila melanogaster (Fruit fly) |
NCBI Taxa ID | 7227 |
Lysine Modification | Position | Peptide | Type | References |
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105 | TSKSKSTKLAKSASK | acetylation | [1] | 108 | SKSTKLAKSASKCKS | acetylation | [1] | 112 | KLAKSASKCKSQGAS | acetylation | [1] | 133 | ARSVADIKMSSIYNR | acetylation | [1] |
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Reference | [1] Proteome-wide mapping of the Drosophila acetylome demonstrates a high degree of conservation of lysine acetylation. Weinert BT, Wagner SA, Horn H, Henriksen P, Liu WR, Olsen JV, Jensen LJ, Choudhary C. Sci Signal. 2011 Jul 26;4(183):ra48. [ PMID: 21791702] |
Functional Description | May function as a negative regulator of the EGFR/Ras/MAPK signaling pathway during eye development. |
Sequence Annotation | ZN_FING 312 362 PHD-type 1. ZN_FING 421 480 PHD-type 2; degenerate. MOD_RES 1346 1346 Phosphothreonine. MOD_RES 1352 1352 Phosphoserine. MOD_RES 1364 1364 Phosphothreonine. MOD_RES 1456 1456 Phosphothreonine. MOD_RES 2880 2880 Phosphoserine. MOD_RES 2881 2881 Phosphoserine. MOD_RES 3104 3104 Phosphoserine. MOD_RES 3110 3110 Phosphoserine. |
Keyword | Alternative splicing; Coiled coil; Complete proteome; Developmental protein; Metal-binding; Nucleus; Phosphoprotein; Reference proteome; Repeat; Zinc; Zinc-finger. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 3241 AA |
Protein Sequence | MSQRGKRGNQ QHHQSHHPPP QQHQRKDVEP QPPPTKRRKG RPPNGATTAA VAEVTGSGPA 60 TGSERVPVLP LCKSKHEEPG AEAGGGGQGR AAAGATSTSK SKSTKLAKSA SKCKSQGASS 120 SSSWQARSVA DIKMSSIYNR SSTEAPAELY RKDLISAMKL PDSEPLANYE YLIVTDPWKQ 180 EWEKGVQVPV NPDSLPEPCV YVLPEPVVSP AHDFKLPKNR YLRITKDEHY SPDLHYLTNV 240 VALAENTCAY DIDPIDEAWL RLYNSDRAQC GAFPINATQF ERVIEELEVR CWEQIQVILK 300 LEEGLGIEFD ENVICDVCRS PDSEEANEMV FCDNCNICVH QACYGITAIP SGQWLCRTCS 360 MGIKPDCVLC PNKGGAMKSN KSGKHWAHVS CALWIPEVSI GCVDRMEPIT KISSIPQSRW 420 SLICVLCRKR VGSCIQCSVK PCKTAYHVTC AFQHGLEMRA IIEEGNAEDG VKLRSYCQKH 480 SMSKGKKENA GSHGGGSASV ASAMQKANRY GSGAGGGADD GNNACGTTGE DPRRRKNHRK 540 TELTSEERNQ ARAQRLQEVE AEFDKHVNFN DISCHLFDVD DDAIVAIYNY WKLKRKSRHN 600 RELIPPKSED VEMIARKQEQ QDMENHKLVV HLRQDLERVR NLCYMVSRRE KLSRSLFKLR 660 EQVFYKQLGV LDEMRLEKQQ TKQEQQQPVM DLNAVIYAND GPTLYDRFYS SVGGQTVPAQ 720 YQDLKYILEQ LMGKLQSGKQ GRGRASQSPN KRKQPAKASP NKKLNNGILS SRTSSPEKTV 780 AGSKVGTTTS KVRSPPGKNP TGRRASKSSA AAATSTHNKS QFHSNIRSST TSHSSSGTIS 840 SGNSSSANGT SSSDSSSGSD SGSESGSSSA GSGVSKRKSS SGSPLKKQSY ARSVEQRQKQ 900 RQRRQNEAVA GASATYPDSR SASSSSDGED ERCRNRQEPE RGARRGPIQS KSVPNRSQAS 960 RSKPTTEADV GEGTGASARR KLSTTTRGLA QMDKDADESV SSDESEELLP LRGERQREST 1020 TTSGLATTGS AIGRNLGQHI YSDSESSSSE QEKDQEEQAT VESNVSDSQN QQTIRTKAAM 1080 KEFVPGTAAT TSSTSQAASS TSKAKNTREG KEGAASIGNS TKTKPNPNAK LYPADLLVVP 1140 QRQAAKKASE NMRSTNLATT LQPDVSDRVR EPDINSISGT AKSKVKDSSS RVSNEADKSS 1200 LEKVRPKEHL QKTVGKTSES APAERGKRGR PPKVPKDARP PSITENDKPA LPTHTQSKPP 1260 SVVATPVSAK SNFAVSLVPQ RQAAKKAAEQ LKSSKPVLES FSTGNDISDK ETVTSATISG 1320 SGSSVPAAST PVKPTRRSSI KEAPITPKEP LSGRRKSKED LLATPIKTTP LVKRRVVVPN 1380 LSSSSSGDSE SSSSSSSSGS SSSSGGSDSD SESQASNSEN PSSREPPVAP AKVPSDSSLV 1440 PKRSPRKSMD KPSALTIAPA SVNVLNIPST RSRQNSTTKS TKVALQKAVQ SVEDDVKCTP 1500 KTNRLQGSMD ECGKQVQLEQ ATKRATRGSK SRPPSPTAKS SPEKTVSRCK SRAEESPKKV 1560 ANLEQEISQR KVASGKGTSS LDKLLNKKQQ QMNHSAQATP PPISPTPPAS ETRIVKDQCD 1620 LKPDEVSIQQ INLGADAQPE PDLDPESAAE AGELPMDIDE ELTTAPTRTQ LSASASKLAD 1680 IIDDERPPAA PLPASPTPTP TSNDEMSDAG SDLSERRRMR WRSRRRRRRR SHEPDEEHTH 1740 HTQHLLNEME MARELEEERK NELLANASKY SASTSSPAVT VIPPDPPEII ELDSNSAEQQ 1800 QQHLHDQPLP PPLVVQSPAA DVVPTVMQQQ LLPSQRPLIE QLPVEHLPIV ETILEMEDSK 1860 FANNFASNLA SVLNPPNQMS LIGSSIDRSK QISEEDSIQA TRNLLEKLRK TKRKAQDDCS 1920 SKEAVDLLPP TPAIPSVFPF HNAADPEDII HAQKEQQHQQ QQQLQSSQTC IYGNSSGPNS 1980 VASLTIKDSP MTANSGSYAN SLTNTPNATP TNATMNNLGY QVNFPNSQPP PTLGLFLEKS 2040 PHQKGACPLS SNGGANVGQP APTPDFVDLA AAAVKNTLGS FRGAATVPTQ SGTGVNAKIN 2100 DYDESTRMQS PFGGMPWNES DLIAERRSSS PSSVSESNDP PQPPPVVTAT ATTARSLAQL 2160 ESCKNFFNSY PSGNAGPGTA ANATAPFNHP PMVNGIDSIP MFNNTNTTQH QPTTPAHQQQ 2220 QQRTPNNQYN GTIYPQLAGI MHPQTTPTEP PSSLYGNGGV GGAVQSTTLP PPAQVNQYPG 2280 TPYSATTLGM ISVQQPALST VPVQTATTPN NPFTLTSPID GKMPTYPAQL LSSCAEAVVA 2340 SMMPPTPPVT ATAKDSPSKR TSVSGSNLSK KQTHKSPQLP QGKSPGKSPR QPLQPPTPPA 2400 PVPVVALPPT KYDPQTHTLQ GKPRQRAPRG SGGSGAPGRG RGRGRGRGRG GGVTSGMAMV 2460 LPPPMSDYGS NTHIVNNLVG TPFEFNNEFD DMAGPGVENL QSLRDRRRSF ELRAPRVQNK 2520 PTTTPTTATT TNPLLHPVLP GPVDMRTYNL GFEAPHSTAS QEAYQNNLLG AFDSGTADQT 2580 LSEFNEEDER QFQSALRATG TGTSPSKQHS GPTALVAPPT GPNPTPAPNL LLHCTEANQM 2640 APNVAATGAA THLVEGSLVE ASLEATSEEV SIDSDSTIPH SKTSTSDARS QIKLKIKSPM 2700 AYPEHYNAMT NSSSLTLTST LVQSSNVVQT TVSTSTVVSA SSAVSGNSRR MRKKELLSLY 2760 VVQKDNHNDD SSCGLPAASD TLPLENLRKS EEEDELSGGN GTKRFKKNSS SRELRALDAN 2820 LALVEEQLLS SGAGACGGGS SGDGRRRSAC SSGSNNDNNG KTGAASSAGK RRGRSKTLES 2880 SEDDHQAPKL KIKIRGLTAN ETPSGVSSVD EGQNYSYEMT RRACPPKKRL TSNFSTLTLE 2940 EIKRDSMNYR KKVMQDFVKG EDSNKRGVVV KDGESLIMPQ PPTKRPKSSK PKKEKKEKKR 3000 QKQQQLILSS STTTMTTTLI ENTASASPGD KPKLILRFGK RKAETTTRTA SLEQPPTLEA 3060 PAPLRFKIAR NSSGGGYIIG TKAEKKDEST ADNTSPITEL PLISPLREAS PQGRLLNSFT 3120 PHSQNANTSP ALLGKDTGTP SPPCLVIDSS KSADVHDSTS LPESGEAAMG VQSSLVNATT 3180 PLCVNVGNYE NSNNSLPSAS GTGSASSNSC NSNSINNNGS GGGRASGEGG LLPLKKDCEV 3240 R 3241 |
Gene Ontology | GO:0005634; C:nucleus; IDA:UniProtKB. GO:0008270; F:zinc ion binding; IEA:InterPro. GO:0042051; P:compound eye photoreceptor development; IMP:UniProtKB. GO:0042059; P:negative regulation of epidermal growth factor receptor signaling pathway; IMP:UniProtKB. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |