CPLM 1.0 - Compendium of Protein Lysine Modification
Tag
Content
CPLM ID
CPLM-025690
UniProt Accession
Q53HU0_HUMAN
;
Q53HU0
Genbank Protein ID
AK222490
Genbank Nucleotide ID
BAD96210.1
Protein Name
Chaperonin containing TCP1, subunit 8 (Theta) variant
Protein Synonyms/Alias
Gene Name
Gene Synonyms/Alias
Created Date
July 27, 2013
Organism
Homo sapiens (Human)
NCBI Taxa ID
9606
Lysine Modification
Position
Peptide
Type
References
20
QMLKEGA
K
HFSGLEE
acetylation
[1]
Reference
[1] Proteome-wide prediction of acetylation substrates.
Basu A, Rose KL, Zhang J, Beavis RC, Ueberheide B, Garcia BA, Chait B, Zhao Y, Hunt DF, Segal E, Allis CD, Hake SB.
Proc Natl Acad Sci U S A. 2009 Aug 18;106(33):13785-90. [
PMID: 19666589
]
Functional Description
Sequence Annotation
Keyword
ATP-binding; Chaperone; Cytoplasm; Nucleotide-binding.
Sequence Source
UniProt (SWISSPROT/TrEMBL); GenBank; EMBL
Protein Length
548 AA
Protein Sequence
MALHVPKAPG FAQMLKEGAK HFSGLEEAVY RNIQACKELA QTTRTAYGPN GMNKMVINHL 60
EKLFVTNDAA TILRELEVQH PAAKMIVMAS HMQEQEVGDG TNFVLVFAGA LLELAEELLR 120
IGLSVSEVIE GYEIACRKAH EILPNLVCCS AKNLRDIDEV SSLLRTSIMS KQYGNEVFLA 180
KLITQACVSI FPDSGHFNVD NIRVCKILGS GISSSSVLHG MVFKKETEGD VTSVKDAKIA 240
VYSCPFDGMI TETKGTVLIK TAEELMNFSK GEENLMDAQV KAIADTGANV VVTGGKVADM 300
ALHYANKYNI MLVRLNSKWD LRRLCKTVGA TALPRLTPPV LEEMGHCDSV YLSEVGDTQV 360
VVFKHEKEDG AISTIVLRGS TDNLMDDIER AVDDGVNTFK VLTRDKRLVP GGGATEIELA 420
KQITSYGETC PGLEQYAIKK FAEAFEAIPR ALAENSGVKA NEVISKLYAV HQEGNKNVGL 480
DIEAEVPAVK DMLEAGILDT YLGKYWAIKL ATNAAVTVLR VDQIIMAKPA GGPKPPSGKK 540
DWDDDQND 548
Gene Ontology
GO:0005737
; C:cytoplasm; IEA:UniProtKB-KW.
GO:0005524
; F:ATP binding; IEA:UniProtKB-KW.
GO:0006457
; P:protein folding; IEA:InterPro.
Interpro
IPR012721
; Chap_CCT_theta.
IPR017998
; Chaperone_TCP-1.
IPR002194
; Chaperonin_TCP-1_CS.
IPR002423
; Cpn60/TCP-1.
IPR027409
; GroEL-like_apical_dom.
IPR027413
; GROEL-like_equatorial.
IPR027410
; TCP-1-like_intermed.
Pfam
PF00118
; Cpn60_TCP1
SMART
PROSITE
PS00750
; TCP1_1
PS00751
; TCP1_2
PS00995
; TCP1_3
PRINTS
PR00304
; TCOMPLEXTCP1.