Tag | Content |
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CPLM ID | CPLM-028286 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | DNA polymerase |
Protein Synonyms/Alias | |
Gene Name | POLE1 |
Gene Synonyms/Alias | |
Created Date | July 27, 2013 |
Organism | Homo sapiens (Human) |
NCBI Taxa ID | 9606 |
Lysine Modification | Position | Peptide | Type | References |
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2121 | EFIKYVCKVLSLDTN | ubiquitination | [1] | 2135 | NITNQVNKLNRDLLR | ubiquitination | [1] |
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Reference | [1] hCKSAAP_UbSite: improved prediction of human ubiquitination sites by exploiting amino acid pattern and properties. Chen Z, Zhou Y, Song J, Zhang Z. Biochim Biophys Acta. 2013 Aug;1834(8):1461-7. [ PMID: 23603789] |
Functional Description | |
Sequence Annotation | |
Keyword | DNA replication; DNA-binding; DNA-directed DNA polymerase; Nucleotidyltransferase; Transferase. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 2297 AA |
Protein Sequence | MSRPLGLKSF PRHKQAPLPL SLTFHGCLLL RRDDGATSSV SALKRLERSQ WTDKMDLRFG 60 FERLKEPGEK TGWLINMHPT EILDEDKRLG SAVDYYFIQD DGSRFKVALP YKPYFYIATR 120 KGCEREVSSF LSKKFQGKIA KVETVPKEDL DLPNHLVGLK RNYIRLSFHT VEDLVKVRKE 180 ISPAVKKNRE QDHASDAYTA LLSSVLQRGG VITDEEETSK KIADQLDNIV DMREYDVPYH 240 IRLSIDLKIH VAHWYNVRYR GNAFPVEITR RDDLVERPDP VVLAFDIETT KLPLKFPDAE 300 TDQIMMISYM IDGQGYLITN REIVSEDIED FEFTPKPEYE GPFCVFNEPD EAHLIQRWFE 360 HVQETKPTIM VTYNGDFFDW PFVEARAAVH GLSMQQEIGF QKDSQGEYKA PQCIHMDCLR 420 WVKRDSYLPV GSHNLKAAAK AKLGYDPVEL DPEDMCRMAT EQPQTLATYS VSDAVATYYL 480 YMKYVHPFIF ALCTIIPMEP DEVLRKGSGT LCEALLMVQA FHANIIFPNK QEQEFNKLTD 540 DGHVLDSETY VGGHVEALES GVFRSDIPCR FRMNPAAFDF LLQRVEKTLR HALEEEEKVP 600 VEQVTNFEEV CDEIKSKLAS LKDVPSRIEC PLIYHLDVGA MYPNIILTNR LQPSAMVDEA 660 TCAACDFNKP GANCQRKMAW QWRGEFMPAS RSEYHRIQHQ LESEKFPPLF PEGPARAFHE 720 LSREEQAKYE KRRLADYCRK AYKKIHITKV EERLTTICQR ENSFYVDTVR AFRDRRYEFK 780 GLHKVWKKKL SAAVEVGDAA EVKRCKNMEV LYDSLQLAHK CILNSFYGYV MRKGARWYSM 840 EMAGIVCFTG ANIITQAREL IEQIGRPLEL DTDGIWCVLP NSFPENFVFK TTNVKKPKVT 900 ISYPGAMLNI MVKEGFTNDQ YQELAEPSSL TYVTRSENSI FFEVDGPYLA MILPASKEEG 960 KKLKKRYAVF NEDGSLAELK GFEVKRRGEL QLIKIFQSSV FEAFLKGSTL EEVYGSVAKV 1020 ADYWLDVLYS KAANMPDSEL FELISENRSM SRKLEDYGEQ KSTSISTAKR LAEFLGDQMV 1080 KDAGLSCRYI ISRKPEGSPV TERAIPLAIF QAEPTVRKHF LRKWLKSSSL QDFDIRAILD 1140 WDYYIERLGS AIQKIITIPA ALQQVKNPVP RVKHPDWLHK KLLEKNDVYK QKKISELFTL 1200 EGRRQVTMAE ASEDSPRPSA PDMEDFGLVK LPHPAAPVTV KRKRVLWESQ EESQDLTPTV 1260 PWQEILGQPP ALGTSQEEWL VWLRFHKKKW QLQARQRLAR RKRQRLESAE GVLRPGAIRD 1320 GPATGLGSFL RRTARSILDL PWQIVQISET SQAGLFRLWA LVGSDLHCIR LSIPRVFYVN 1380 QRVAKAEEGA SYRKVNRVLP RSNMVYNLYE YSVPEDMYQE HINEINAELS APDIEGVYET 1440 QVPLLFRALV HLGCVCVVNK QLVRHLSGWE AETFALEHLE MRSLAQFSYL EPGSIRHIYL 1500 YHHAQAHKAL FGIFIPSQRR ASVFVLDTVR TDQMPSLGAL YSAEHGLLLE KVGPELLPPP 1560 KHTFEVRAET DLKTICRAIQ RFLLAYKEER RGPTLIAVQS SWELKRLASE IPVLEEFPLV 1620 PICVADKINY GVLDWQRHGA RRMIRHYLNL DTCLSQAFEM SRYFHIPIGN LPEDISTFGS 1680 DLFFARHLQR HNHLLWLSPT ARPDLGGKEA DDNCLVMEFD DQATVEINSS GCYSTVCVEL 1740 DLQNLAVNTI LQSHHVNDME GADSMGISFD VIQQASLEDM ITGGQAASAP ASYDETALCS 1800 NTFRILKSMV VGWVKEITQY HNIYADNQVM HFYRWLRSPS SLLHDPALHR TLHNMMKKLF 1860 LQLIAEFKRL GSSVIYANFN RIILCTKKRR VEDAIAYVEY ITSSIHSKET FHSLTISFSR 1920 CWEFLLWMDP SNYGGIKGKV SSRIHCGLQD SQKAGGAEDE QENEDDEEER DGEEEEEAEE 1980 SNVEDLLENN WNILQFLPQA ASCQNYFLMI VSAYIVAVYH CMKDGLRRSA PGSTPVRRRG 2040 ASQLSQEAEG AVGALPGMIT FSQDYVANEL TQSFFTITQK IQKKVTGSRN STELSEMFPV 2100 LPGSHLLLNN PALEFIKYVC KVLSLDTNIT NQVNKLNRDL LRLVDVGEFS EEAQFRDPCR 2160 SYVLPEVICR SCNFCRDLDL CKDSSFSEDG AVLPQWLCSN CQAPYDSSAI EMTLVEVLQK 2220 KLMAFTLQDL VCLKCRGVKE TSMPVYCTCA GDFALTIHTQ VFMEQIGIFR NIAQHYGMSY 2280 LLETLEWLLQ KNPQLGH 2297 |
Gene Ontology | |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |