CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-013744
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Cytospin-B 
Protein Synonyms/Alias
 Nuclear structure protein 5; NSP5; Sperm antigen HCMOGT-1; Sperm antigen with calponin homology and coiled-coil domains 1 
Gene Name
 SPECC1 
Gene Synonyms/Alias
 CYTSB; NSP5 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
897LPLSDILKGRTETLKubiquitination[1]
964AREYGGSKRNALLKWacetylation[2]
970SKRNALLKWCQKKTQacetylation[2]
Reference
 [1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [2] Regulation of cellular metabolism by protein lysine acetylation.
 Zhao S, Xu W, Jiang W, Yu W, Lin Y, Zhang T, Yao J, Zhou L, Zeng Y, Li H, Li Y, Shi J, An W, Hancock SM, He F, Qin L, Chin J, Yang P, Chen X, Lei Q, Xiong Y, Guan KL.
 Science. 2010 Feb 19;327(5968):1000-4. [PMID: 20167786] 
Functional Description
  
Sequence Annotation
 DOMAIN 962 1064 CH.
 MOD_RES 112 112 Phosphoserine (By similarity).
 MOD_RES 120 120 Phosphoserine (By similarity).
 MOD_RES 131 131 Phosphoserine.
 MOD_RES 134 134 Phosphoserine.
 MOD_RES 138 138 Phosphoserine.
 MOD_RES 142 142 Phosphothreonine.
 MOD_RES 218 218 Phosphoserine.
 MOD_RES 241 241 Phosphoserine.
 MOD_RES 425 425 Phosphoserine.
 MOD_RES 847 847 Phosphoserine.
 MOD_RES 863 863 Phosphoserine.
 MOD_RES 912 912 Phosphoserine.  
Keyword
 Alternative splicing; Chromosomal rearrangement; Coiled coil; Complete proteome; Nucleus; Phosphoprotein; Polymorphism; Proto-oncogene; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1068 AA 
Protein Sequence
MRSAAKPWNP AIRAGGHGPD RVRPLPAASS GMKSSKSSTS LAFESRLSRL KRASSEDTLN 60
KPGSTAASGV VRLKKTATAG AISELTESRL RSGTGAFTTT KRTGIPAPRE FSVTVSRERS 120
VPRGPSNPRK SVSSPTSSNT PTPTKHLRTP STKPKQENEG GEKAALESQV RELLAEAKAK 180
DSEINRLRSE LKKYKEKRTL NAEGTDALGP NVDGTSVSPG DTEPMIRALE EKNKNFQKEL 240
SDLEEENRVL KEKLIYLEHS PNSEGAASHT GDSSCPTSIT QESSFGSPTG NQMSSDIDEY 300
KKNIHGNALR TSGSSSSDVT KASLSPDASD FEHITAETPS RPLSSTSNPF KSSKCSTAGS 360
SPNSVSELSL ASLTEKIQKM EENHHSTAEE LQATLQELSD QQQMVQELTA ENEKLVDEKT 420
ILETSFHQHR ERAEQLSQEN EKLMNLLQER VKNEEPTTQE GKIIELEQKC TGILEQGRFE 480
REKLLNIQQQ LTCSLRKVEE ENQGALEMIK RLKEENEKLN EFLELERHNN NMMAKTLEEC 540
RVTLEGLKME NGSLKSHLQG EKQKATEASA VEQTAESCEV QEMLKVARAE KDLLELSCNE 600
LRQELLKANG EIKHVSSLLA KVEKDYSYLK EICDHQAEQL SRTSLKLQEK ASESDAEIKD 660
MKETIFELED QVEQHRAVKL HNNQLISELE SSVIKLEEQK SDLERQLKTL TKQMKEETEE 720
WRRFQADLQT AVVVANDIKC EAQQELRTVK RKLLEEEEKN ARLQKELGDV QGHGRVVTSR 780
AAPPPVDEEP ESSEVDAAGR WPGVCVSRTS PTPPESATTV KSLIKSFDLG RPGGAGQNIS 840
VHKTPRSPLS GIPVRTAPAA AVSPMQRHST YSSVRPASRG VTQRLDLPDL PLSDILKGRT 900
ETLKPDPHLR KSPSLESLSR PPSLGFGDTR LLSASTRAWK PQSKLSVERK DPLAALAREY 960
GGSKRNALLK WCQKKTQGYA NIDITNFSSS WSDGLAFCAL LHTYLPAHIP YQELNSQEKK 1020
RNLLLAFEAA ESVGIKPSLE LSEMLYTDRP DWQSVMQYVA QIYKYFET 1068 
Gene Ontology
 GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
 GO:0007155; P:cell adhesion; IDA:MGI. 
Interpro
 IPR001715; CH-domain. 
Pfam
 PF00307; CH 
SMART
 SM00033; CH 
PROSITE
 PS50021; CH 
PRINTS