| Tag | Content |
|---|
| CPLM ID | CPLM-000999 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Zinc finger protein 354A |
Protein Synonyms/Alias | Transcription factor 17; TCF-17; Zinc finger protein eZNF |
Gene Name | ZNF354A |
Gene Synonyms/Alias | EZNF; HKL1; TCF17 |
Created Date | July 27, 2013 |
Organism | Homo sapiens (Human) |
NCBI Taxa ID | 9606 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 268 | QITHTGEKPYICKEC | ubiquitination | [1] | | 273 | GEKPYICKECGKAFT | ubiquitination | [1] |
|
Reference | [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments. Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA. Mol Cell Proteomics. 2013 Mar;12(3):825-31. [ PMID: 23266961] |
Functional Description | |
Sequence Annotation | DOMAIN 14 85 KRAB.
ZN_FING 214 236 C2H2-type 1.
ZN_FING 242 264 C2H2-type 2.
ZN_FING 270 292 C2H2-type 3.
ZN_FING 298 320 C2H2-type 4.
ZN_FING 354 376 C2H2-type 5.
ZN_FING 382 404 C2H2-type 6.
ZN_FING 410 432 C2H2-type 7.
ZN_FING 438 460 C2H2-type 8.
ZN_FING 464 488 C2H2-type 9.
ZN_FING 494 516 C2H2-type 10.
ZN_FING 522 544 C2H2-type 11.
ZN_FING 550 572 C2H2-type 12.
ZN_FING 578 600 C2H2-type 13. |
Keyword | Activator; Complete proteome; DNA-binding; Metal-binding; Nucleus; Reference proteome; Repeat; Transcription; Transcription regulation; Zinc; Zinc-finger. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 605 AA |
Protein Sequence | MAAGQREARP QVSLTFEDVA VLFTRDEWRK LAPSQRNLYR DVMLENYRNL VSLGLPFTKP 60
KVISLLQQGE DPWEVEKDGS GVSSLGSKSS HKTTKSTQTQ DSSFQGLILK RSNRNVPWDL 120
KLEKPYIYEG RLEKKQDKKG SFQIVSATHK KIPTIERSHK NTELSQNFSP KSVLIRQQIL 180
PREKTPPKCE IQGNSLKQNS QLLNQPKITA DKRYKCSLCE KTFINTSSLR KHEKNHSGEK 240
LFKCKECSKA FSQSSALIQH QITHTGEKPY ICKECGKAFT LSTSLYKHLR THTVEKSYRC 300
KECGKSFSRR SGLFIHQKIH AEENPCKYNP GRKASSCSTS LSGCQRIHSR KKSYLCNECG 360
NTFKSSSSLR YHQRIHTGEK PFKCSECGRA FSQSASLIQH ERIHTGEKPY RCNECGKGFT 420
SISRLNRHRI IHTGEKFYNC NECGKALSSH STLIIHERIH TGEKPCKCKV CGKAFRQSSA 480
LIQHQRMHTG ERPYKCNECG KTFRCNSSLS NHQRIHTGEK PYRCEECGIS FGQSSALIQH 540
RRIHTGEKPF KCNTCGKTFR QSSSRIAHQR IHTGEKPYEC NTCGKLFNHR SSLTNHYKIH 600
IEEDP 605 |
Gene Ontology | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. GO:0003677; F:DNA binding; IEA:UniProtKB-KW. GO:0008270; F:zinc ion binding; IEA:InterPro. GO:0006357; P:regulation of transcription from RNA polymerase II promoter; TAS:ProtInc. GO:0007605; P:sensory perception of sound; TAS:ProtInc. GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |