Tag | Content |
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CPLM ID | CPLM-010862 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Glutathione S-transferase theta-1 |
Protein Synonyms/Alias | GST 5-5; GST class-theta-1; Glutathione S-transferase 5 |
Gene Name | Gstt1 |
Gene Synonyms/Alias | |
Created Date | July 27, 2013 |
Organism | Rattus norvegicus (Rat) |
NCBI Taxa ID | 10116 |
Lysine Modification | Position | Peptide | Type | References |
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22 | RAIYIFAKKNNIPFQ | acetylation | [1] | 79 | LYLAHKYKVPDHWYP | acetylation | [1] |
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Reference | [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns. Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV. Cell Rep. 2012 Aug 30;2(2):419-31. [ PMID: 22902405] |
Functional Description | Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Also binds steroids, bilirubin, carcinogens and numerous organic anions. Has dichloromethane dehalogenase activity. |
Sequence Annotation | DOMAIN 2 82 GST N-terminal. DOMAIN 88 223 GST C-terminal. REGION 53 54 Glutathione binding (By similarity). REGION 66 67 Glutathione binding (By similarity). BINDING 40 40 Glutathione (By similarity). |
Keyword | Complete proteome; Cytoplasm; Direct protein sequencing; Reference proteome; Transferase. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 240 AA |
Protein Sequence | MVLELYLDLL SQPCRAIYIF AKKNNIPFQM HTVELRKGEH LSDAFAQVNP MKKVPAMKDG 60 GFTLCESVAI LLYLAHKYKV PDHWYPQDLQ ARARVDEYLA WQHTTLRRSC LRTLWHKVMF 120 PVFLGEQIRP EMLAATLADL DVNVQVLEDQ FLQDKDFLVG PHISLADVVA ITELMHPVGG 180 GCPVFEGRPR LAAWYRRVEA AVGKDLFLEA HEVILKVRDC PPADPVIKQK LMPRVLTMIQ 240 |
Gene Ontology | GO:0005829; C:cytosol; IDA:RGD. GO:0004602; F:glutathione peroxidase activity; IDA:RGD. GO:0004364; F:glutathione transferase activity; IDA:UniProtKB. GO:0006749; P:glutathione metabolic process; IDA:UniProtKB. GO:0042493; P:response to drug; IEP:RGD. GO:0014070; P:response to organic cyclic compound; IEP:RGD. |
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