CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-028879
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Neuroblastoma breakpoint family member 20 
Protein Synonyms/Alias
 Neuroblastoma breakpoint family, member 10 
Gene Name
 NBPF10 
Gene Synonyms/Alias
 NBPF20; RP11-89F3.1-001 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
627SRELLDEKGPEVLQDubiquitination[1, 2]
702SRELLDEKEPEVLQDubiquitination[2, 3]
Reference
 [1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [2] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [3] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 4621 AA 
Protein Sequence
MVVSAGPWSS EKAEMNILEI NEKLRPQLAE NKQQFGNLKE RCFVTQLAGF LANQQKKYNY 60
EECKDLIKFM LRNERQFKEE KLAEQLKQAE ELRQYKVLVH SQERELTQLR EKLREGRDAS 120
RSLNEHLQAL LTLDEPDKSQ GQDLQEQLAE GCRLAQHLVQ KLSPENDEDE DEDVQVEEAE 180
KVQKSSAPRE VQKTEESKVP EDSLEECAIT CSNSHGPCDS NQPHKNIKIT FEEDEVNSTL 240
VVDRESSHDE CQDALNILPV PGPTSSATNV SMVVSAGPLS SEKAEMNILE INEKLHPQLA 300
EKKQQFRNLK ERCFVTQLAG FLANQQKKYK YEECKDLIKS MLRNERQFKE EKLAEQLKQA 360
EELRQYKVLV HAQERELTQL REKLREGRDA SRSLNEHLQA LLTPDEPDKS QGQDLQEQLA 420
EGCRLAQHLV QKLSPENDND DDEDVQVELA EKVQKSSAPR EMQKAEEKEV PEDSQEECAI 480
TYSNSHGPYD SNQPHRKTKI TFEEDKVDST LIGSSSHVEW EDAVHIIPEN ESDDEEEEEK 540
GPVSPRNLQE SEEEEVPQES WDEGYSTLSI PPEMLASYQS YSSTFHSLEE QQVCMAVDIG 600
RHRWDQVKKE DQEATGPRLS RELLDEKGPE VLQDSLDRCY STPSGCLELT DSCQPYRSAF 660
YVLEQQRIGL AVDMDEIEKY QEVEEDQDPS CPRLSRELLD EKEPEVLQDS LDRCYSTPSG 720
YLELPDLGQP YSSAVYSLEE QYLGLALDVD RTKKDQEEEE DQGPPCPRLS RELLEVVEPE 780
VLQDSLDRCY STPSSCLEQP DSCQPYGSSF YALEEKHVGF SLDVGEIEKK GKGKKRRGRR 840
SKKERRRGRK EGEEDQNPPC PRLSRELLDE KGPEVLQDSL DRSYSTPSGC LELTDSCQPY 900
RSAFYVLEQQ RVGLAVDMDE IEKYQEVEED QDPSCPRLSR ELLDEKEPEV LQDSLDRCYS 960
TPSGYLELPD LGQPYSSAVY SLEEQYLGLA LDVDRTKKDQ EEEEDQGPPC PRLSRELLEV 1020
VEPEVLQDSL DRCYSTPSSC LEQPDSCQPY GSSFYALEEK HVGFSLDVGE IEKKGKGKKR 1080
RGRRSKKERR RGRKEGEEDQ NPPCPRLSRE LLDEKGPEVL QDSLDRCYST PSGCLELTDS 1140
CQPYRSAFYV LEQQRVGLAV DMDEIEKYQE VEEDQDPSCP RLSRELLDEK EPEVLQDSLD 1200
RCYSTPSGYL ELPDLGQPYS SAVYSLEEQY LGLALDVDRT KKDQEEEEDQ GPPCPRLSRE 1260
LLEVVEPEVL QDSLDRCYST PSSCLEQPDS CQPYGSSFYA LEEKHVGFSL DVGEIEKKGK 1320
GKKRRGRRSK KERRRGRKEG EEDQNPPCPR LSRELLDEKG PEVLQDSLDR SYSTPSGCLE 1380
LTDSCQPYRS AFYVLEQQRV GLAVDMDEIE KYQEVEEDQD PSCPRLSREL LDEKEPEVLQ 1440
DSLDRCYSTP SGYLELPDLG QPYSSAVYSL EEQYLGLALD VDRTKKDQEE EEDQGPPCPR 1500
LSRELLEVVE PEVLQDSLDR CYSTPSSCLE QPDSCQPYGS SFYALEEKHV GFSLDVGEIE 1560
KKGKGKKRRG RRSKKERRRG RKEGEEDQNP PCPRLSRELL DEKGPEVLQD SLDRCYSTPS 1620
GCLELTDSCQ PYRSAFYVLE QQRVGLAVDM DEIEKYQEVE EDQDPSCPRL SRELLDEKEP 1680
EVLQDSLDRC YSTPSGYLEL PDLGQPYSSA VYSLEEQYLG LALDVDRTKK DQEEEEDQGP 1740
PCPRLSRELL EVVEPEVLQD SLDRCYSTPS SCLEQPDSCQ PYGSSFYALE EKHVGFSLDV 1800
GEIEKKGKGK KRRGRRSKKE RRRGRKEGEE DQNPPCPRLS RELLDEKGPE VLQDSLDRSY 1860
STPSGCLELT DSCQPYRSAF YVLEQQRVGL AVDMDEIEKY QEVEEDQDPS CPRLSRELLD 1920
EKEPEVLQDS LDRCYSTPSG YLELPDLGQP YSSAVYSLEE QYLGLALDVD RTKKDQEEEE 1980
DQGPPCPRLS RELLEVVEPE VLQDSLDRCY STPSSCLEQP DSCQPYGSSF YALEEKHVGF 2040
SLDVGEIEKK GKGKKRRGRR SKKERRRGRK EGEEDQNPPC PRLSRELLDE KGPEVLQDSL 2100
DRSYSTPSGC LELTDSCQPY RSAFYVLEQQ RVGLAVDMDE IEKYQEVEED QDPSCPRLSR 2160
ELLDEKEPEV LQDSLDRCYS TPSGYLELPD LGQPYSSAVY SLEEQYLGLA LDVDRTKKDQ 2220
EEEEDQGPPC PRLSRELLEV VEPEVLQDSL DRCYSTPSSC LEQPDSCQPY GSSFYALEEK 2280
HVGFSLDVGE IEKKGKGKKR RGRRSKKERR RGRKEGEEDQ NPPCPRLSRE LLDEKGPEVL 2340
QDSLDRSYST PSGCLELTDS CQPYRSAFYV LEQQRVGLAV DMDEIEKYQE VEEDQDPSCP 2400
RLSRELLDEK EPEVLQDSLD RCYSTPSGYL ELPDLGQPYS SAVYSLEEQY LGLALDVDRT 2460
KKDQEEEEDQ GPPCPRLSRE LLEVVEPEVL QDSLDRCYST PSSCLEQPDS CQPYGSSFYA 2520
LEEKHVGFSL DVGEIEKKGK GKKRRGRRSK KERRRGRKEG EEDQNPPCPR LSRELLDEKG 2580
PEVLQDSLDR SYSTPSGCLE LTDSCQPYRS AFYVLEQQRV GLAVDMDEIE KYQEVEEDQD 2640
PSCPRLSREL LDEKEPEVLQ DSLDRCYSTP SGYLELPDLG QPYSSAVYSL EEQYLGLALD 2700
VDRTKKDQEE EEDQGPPCPR LSRELLEVVE PEVLQDSLDR CYSTPSSCLE QPDSCQPYGS 2760
SFYALEEKHV GFSLDVGEIE KKGKGKKRRG RRSKKERRRG RKEGEEDQNP PCPRLSRELL 2820
DEKEPEVLQD SLDRCYSTPS GYLELPDLGQ PYSSAVYSLE EQYLGLALDV DRTKKDQEEE 2880
EDQGPPCPRL SRELLEVVEP EVLQDSLDRC YSTPSSCLEQ PDSCQPYGSS FYALEEKHVG 2940
FSLDVGEIEK KGKGKKRRGR RSKKERRRGR KEGEEDQNPP CPRLSRELLD EKEPEVLQDS 3000
LDRCYSTPSG YLELPDLGQP YSSAVYSLEE QYLGLALDVD RTKKDQEEEE DQGPPCPRLS 3060
RELLEVVEPE VLQDSLDRCY STPSSCLEQP DSCQPYGSSF YALEEKHVGF SLDVGEIEKK 3120
GKGKKRRGRR SKKERRRGRK EGEEDQNPPC PRLSRELLDE KEPEVLQDSL DRCYSTPSGY 3180
LELPDLGQPY SSAVYSLEEQ YLGLALDVDR TKKDQEEEED QGPPCPRLSR ELLEVVEPEV 3240
LQDSLDRCYS TPSSCLEQPD SCQPYGSSFY ALEEKHVGFS LDVGEIEKKG KGKKRRGRRS 3300
KKERRRGRKE GEEDQNPPCP RLSRELLDEK GPEVLQDSLD RCYSTPSGCL ELTDSCQPYR 3360
SAFYVLEQQR VGLAVDMDEI EKYQEVEEDQ DPSCPRLSRE LLDEKEPEVL QDSLDRCYST 3420
PSGYLELPDL GQPYSSAVYS LEEQYLGLAL DVDRTKKDQE EEEDQGPPCP RLSRELLEVV 3480
EPEVLQDSLD RCYSTPSSCL EQPDSCQPYG SSFYALEEKH VGFSLDVGEI EKKGKGKKRR 3540
GRRSKKERRR GRKEGEEDQN PPCPRLSREL LDEKGPEVLQ DSLDRCYSTP SGCLELTDSC 3600
QPYRSAFYVL EQQRVGLAVD MDEIEKYQEV EEDQDPSCPR LSRELLDEKE PEVLQDSLDR 3660
CYSTPSGYLE LPDLGQPYSS AVYSLEEQYL GLALDVDRTK KDQEEEEDQG PPCPRLSREL 3720
LEVVEPEVLQ DSLDRCYSTP SSCLEQPDSC QPYGSSFYAL EEKHVGFSLD VGEIEKKGKG 3780
KKRRGRRSKK ERRRGRKEGE EDQNPPCPRL SRELLDEKGP EVLQDSLDRC YSTPSGCLEL 3840
TDSCQPYRSA FYVLEQQRVG LAVDMDEIEK YQEVEEDQDP SCPRLSRELL DEKEPEVLQD 3900
SLDRCYSTPS GYLELPDLGQ PYSSAVYSLE EQYLGLALDV DRTKKDQEEE EDQGPPCPRL 3960
SRELLEVVEP EVLQDSLDRC YSTPSSCLEQ PDSCQPYGSS FYALEEKHVG FSLDVGEIEK 4020
KGKGKKRRGR RSKKERRRGR KEGEEDQTPP CPRLSRELLD EKGPEVLQDS LDRCYSTPSG 4080
CLELTDSCQP YRSAFYVLEQ QRVGLAVDMD EIEKYQEVEE DQDPSCPRLS RELLDEKEPE 4140
VLQDSLDRCY STPSGYLELP DLGQPYSSAV YSLEEQYLGL ALDVDRTKKD QEEEEDQGPP 4200
CPRLSRELLE VVEPEVLQDS LDRCYSTPSS CLEQPDSCQP YGSSFYALEE KHVGFSLDVG 4260
EIEKKGKGKK RRGRRSKKER RRGRKEGEED QNPPCPRLSR ELLDEKGPEV LQDSLDRCYS 4320
TPSGCLELTD SCQPYRSAFY VLEQQRVGLA VDMDEIEKYQ EVEEDQDPSC PRLSRELLDE 4380
KEPEVLQDSL DRCYSTPSGY LELPDLGQPY SSAVYSLEEQ YLGLALDVDR TKKDQEEEED 4440
QGPPCPRLSR ELLEVVEPEV LQDSLDRCYS TPSSCLEQPD SCQPYGSSFY ALEEKHVGFS 4500
LDVGEIEKKG KGKKRRGRRS KKKRRRGRKE GEEDQNPPCP RLNGVLMEVE EPEVLQDSLD 4560
GCYSTPSMYF ELPDSFQHYR SVFYSFEEQH ISFALYVDNR FFTLTVTSLH LVFQMGVIFP 4620
Q 4621 
Gene Ontology
  
Interpro
 IPR010630; NBPF_dom. 
Pfam
 PF06758; DUF1220 
SMART
  
PROSITE
 PS51316; NBPF 
PRINTS