CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-032628
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Asparaginyl-tRNA synthetase, putative 
Protein Synonyms/Alias
  
Gene Name
 TGVEG_017780 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Toxoplasma gondii 
NCBI Taxa ID
 5811 
Lysine Modification
Position
Peptide
Type
References
242GEFPQLLKCGAGCSFacetylation[1]
288LGMTDAAKYPLAKKEacetylation[2]
585MKLNEDGKTVRAMDVacetylation[2]
Reference
 [1] Protein intrinsic disorder in the acetylome of intracellular and extracellular Toxoplasma gondii.
 Xue B, Jeffers V, Sullivan WJ, Uversky VN.
 Mol Biosyst. 2013 Apr 5;9(4):645-57. [PMID: 23403842]
 [2] Lysine acetylation is widespread on proteins of diverse function and localization in the protozoan parasite Toxoplasma gondii.
 Jeffers V, Sullivan WJ Jr.
 Eukaryot Cell. 2012 Jun;11(6):735-42. [PMID: 22544907] 
Functional Description
  
Sequence Annotation
  
Keyword
 Aminoacyl-tRNA synthetase; ATP-binding; Complete proteome; Ligase; Nucleotide-binding; Protein biosynthesis; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 676 AA 
Protein Sequence
MPRRCWQLFV CCSVREFPVS VASRLLLPLL FVLASARNSA LLYSSALTLR SSAAPLAFSS 60
AGCRFRGPLH RPWFPVSLPP PDQAYLSRNS ASGTSPRSIR QFPVPSGLAL PTSVPLCART 120
LPPLSRHFAS AGTMAQPQGE SKSFTPGHLE DQVPTSCKQA IPVFGCGSTR VRLAALLDGG 180
EASVEKFVNR ETPVTVCGWS RSVRKQGGGS LCFVVLSDGS TSSNLQVVVE AGIGGEFPQL 240
LKCGAGCSFR FTGDIVKSPA KGQAVELAVR DPSKGHRFEI LGMTDAAKYP LAKKEHTREY 300
LREIAHLRPR SYLIGAVMRV RSNLAMATHR FFQDRGFLYI HTPIVTASDC EGAGEMFQVS 360
TLLPPPPPET RENEKKTDGA APKDAAAAAA EPLIPLKKDK KGVDYSRDFF GRPAFLTVSG 420
QLAVEPYCCS LSDVYTFGPT FRAENSHTSR HLAEFWMVEP EIAFATLEDN MVVAEAYVKF 480
CVQWVLDNCR ADIEWFQKNQ EEGLIARLEN ILAEPFARVS YTEAIEVLKA EEPKAQFKEK 540
VEWGMDMGSE HERYLTENVY KKPCIVYNYP KDIKAFYMKL NEDGKTVRAM DVLVPKIGEL 600
VGGSQREDDR DRLAAMIAAK DLDPKPYWWY MELREYGTIP HAGFGLGFER LVMLVTGIEN 660
IRDTIPYPRY PGHAEF 676 
Gene Ontology
 GO:0005737; C:cytoplasm; IEA:InterPro.
 GO:0004816; F:asparagine-tRNA ligase activity; IEA:EC.
 GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
 GO:0003676; F:nucleic acid binding; IEA:InterPro.
 GO:0006421; P:asparaginyl-tRNA aminoacylation; IEA:InterPro. 
Interpro
 IPR004364; aa-tRNA-synt_II.
 IPR018150; aa-tRNA-synt_II-like.
 IPR006195; aa-tRNA-synth_II.
 IPR004522; Asn-tRNA-ligase_IIb.
 IPR002312; Asp/Asn-tRNA-synth_IIb.
 IPR012340; NA-bd_OB-fold.
 IPR004365; NA-bd_OB_tRNA-helicase. 
Pfam
 PF00152; tRNA-synt_2
 PF01336; tRNA_anti 
SMART
  
PROSITE
 PS50862; AA_TRNA_LIGASE_II 
PRINTS
 PR01042; TRNASYNTHASP.