UniProt Accession

 RAD51_YEAST; P25454; D3DM03 

Genbank Protein ID

 X64270; M88470; D10023; U18839; BK006939 

Genbank Nucleotide ID

 CAA45563.1; AAA34948.1; BAA00913.1; AAB64650.1; DAA07757.1 

Protein Name

 DNA repair protein RAD51 

Protein Synonyms/Alias

  

Gene Name

 RAD51 

Gene Synonyms/Alias

 YER095W 

Created Date

 July 27, 2013 

Organism

 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 

NCBI Taxa ID

 559292 

Lysine Modification

Position	Peptide	Type	References
131	ISEAKADKLLNEAAR	ubiquitination	[1]

Reference

 [1] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.
 Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, Villén J.
 Nat Methods. 2013 Jul;10(7):676-82. [PMID: 23749301] 

Functional Description

 Required both for recombination and for the repair of DNA damage caused by X-rays. Its function may be modulated by interaction with other repair proteins. RAD52 interacts directly with RAD51, via its C-terminus. Forms a nucleoprotein filament with DNA as an early intermediate in recombination. 

Sequence Annotation

 NP_BIND 185 192 ATP (Potential).  

Keyword

 3D-structure; ATP-binding; Chromosome; Complete proteome; DNA damage; DNA recombination; DNA repair; Nucleotide-binding; Nucleus; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 400 AA 

Protein Sequence

Gene Ontology

 GO:0000794; C:condensed nuclear chromosome; IDA:SGD.
 GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
 GO:0003684; F:damaged DNA binding; IEA:InterPro.
 GO:0008094; F:DNA-dependent ATPase activity; IDA:SGD.
 GO:0000150; F:recombinase activity; IDA:SGD.
 GO:0003697; F:single-stranded DNA binding; IDA:SGD.
 GO:0000724; P:double-strand break repair via homologous recombination; TAS:BHF-UCL.
 GO:0030491; P:heteroduplex formation; IDA:SGD.
 GO:0000709; P:meiotic joint molecule formation; IMP:SGD.
 GO:0042148; P:strand invasion; IDA:SGD.
 GO:0000722; P:telomere maintenance via recombination; IMP:SGD. 

Interpro

 IPR003593; AAA+_ATPase.
 IPR011941; DNA_recomb/repair_Rad51.
 IPR013632; DNA_recomb/repair_Rad51_C.
 IPR016467; DNA_recomb/repair_RecA-like.
 IPR020588; DNA_recomb_RecA/RadB_ATP-bd.
 IPR010995; DNA_repair_Rad51/TF_NusA_a-hlx.
 IPR003583; Hlx-hairpin-Hlx_DNA-bd_motif.
 IPR027417; P-loop_NTPase.
 IPR020587; RecA_monomer-monomer_interface. 

Pfam

 PF08423; Rad51 

SMART

 SM00382; AAA
 SM00278; HhH1 

PROSITE

 PS50162; RECA_2
 PS50163; RECA_3 

PRINTS