CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-001760
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 NADH dehydrogenase 
Protein Synonyms/Alias
  
Gene Name
 ndh 
Gene Synonyms/Alias
 b1109; JW1095 
Created Date
 July 27, 2013 
Organism
 Escherichia coli (strain K12) 
NCBI Taxa ID
 83333 
Lysine Modification
Position
Peptide
Type
References
35LGRKKKAKITLVDRNacetylation[1]
103IAELRDEKGELLVPEacetylation[1]
194AELHNAVKQLHSYGYacetylation[1]
202QLHSYGYKGLTNEALacetylation[1]
238AAHNELTKLGVRVLTacetylation[1]
283IKAPDFLKDIGGLETacetylation[1]
352ILAQMNGKPLKNYQYacetylation[1]
360PLKNYQYKDHGSLVSacetylation[1]
Reference
 [1] Acetyl-Phosphate Is a Critical Determinant of Lysine Acetylation in E. coli.
 Weinert BT, Iesmantavicius V, Wagner SA, Schölz C, Gummesson B, Beli P, Nyström T, Choudhary C.
 Mol Cell. 2013 Jul 25;51(2):265-72. [PMID: 23830618] 
Functional Description
 Transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. Does not couple the redox reaction to proton translocation. 
Sequence Annotation
 NP_BIND 7 42 FAD (By similarity).
 NP_BIND 171 208 NAD (By similarity).  
Keyword
 3D-structure; Cell membrane; Complete proteome; Direct protein sequencing; Electron transport; FAD; Flavoprotein; Membrane; NAD; Oxidoreductase; Reference proteome; Transport; Ubiquinone. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 434 AA 
Protein Sequence
MTTPLKKIVI VGGGAGGLEM ATQLGHKLGR KKKAKITLVD RNHSHLWKPL LHEVATGSLD 60
EGVDALSYLA HARNHGFQFQ LGSVIDIDRE AKTITIAELR DEKGELLVPE RKIAYDTLVM 120
ALGSTSNDFN TPGVKENCIF LDNPHQARRF HQEMLNLFLK YSANLGANGK VNIAIVGGGA 180
TGVELSAELH NAVKQLHSYG YKGLTNEALN VTLVEAGERI LPALPPRISA AAHNELTKLG 240
VRVLTQTMVT SADEGGLHTK DGEYIEADLM VWAAGIKAPD FLKDIGGLET NRINQLVVEP 300
TLQTTRDPDI YAIGDCASCP RPEGGFVPPR AQAAHQMATC AMNNILAQMN GKPLKNYQYK 360
DHGSLVSLSN FSTVGSLMGN LTRGSMMIEG RIARFVYISL YRMHQIALHG YFKTGLMMLV 420
GSINRVIRPR LKLH 434 
Gene Ontology
 GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
 GO:0050660; F:flavin adenine dinucleotide binding; IDA:EcoCyc.
 GO:0008137; F:NADH dehydrogenase (ubiquinone) activity; IDA:EcoCyc.
 GO:0019646; P:aerobic electron transport chain; IDA:EcoCyc. 
Interpro
 IPR013027; FAD_pyr_nucl-diS_OxRdtase.
 IPR023753; Pyr_nucl-diS_OxRdtase_FAD/NAD.
 IPR001327; Pyr_OxRdtase_NAD-bd_dom. 
Pfam
 PF00070; Pyr_redox
 PF07992; Pyr_redox_2 
SMART
  
PROSITE
  
PRINTS
 PR00368; FADPNR.