CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-025844
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Stearoyl-CoA desaturase variant 
Protein Synonyms/Alias
  
Gene Name
  
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
169RDHRAHHKFSETHADubiquitination[1]
203KHPAVKEKGSTLDLSubiquitination[1]
216LSDLEAEKLVMFQRRubiquitination[1]
348YDRKKVSKAAILARIubiquitination[1]
Reference
 [1] Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass.
 Povlsen LK, Beli P, Wagner SA, Poulsen SL, Sylvestersen KB, Poulsen JW, Nielsen ML, Bekker-Jensen S, Mailand N, Choudhary C.
 Nat Cell Biol. 2012 Oct;14(10):1089-98. [PMID: 23000965] 
Functional Description
  
Sequence Annotation
  
Keyword
 Fatty acid biosynthesis; Fatty acid metabolism; Iron; Lipid biosynthesis; Lipid metabolism; Membrane; Oxidoreductase; Transmembrane. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 366 AA 
Protein Sequence
SRHPRAKMPA HLLQDDISSS YTTTTTITAP PSRVLQNGGD KLETMPLYLE DDIRPDIKDD 60
IYDPTYKDKE GPSPKVEYVW RNIILMSLLH LGALYGITLI PTCKFYTWLW GVFYYFVSAL 120
GITAGAHRLW SHRSYKARLP LRLFLIIANT MAFQNDVYEW ARDHRAHHKF SETHADPHNS 180
RRGFFFSHVG WLLVRKHPAV KEKGSTLDLS DLEAEKLVMF QRRYYKPGLL LMCFILPTLV 240
PWYFWGETFQ NSVFVATFLR YAVVLNATWL VNSAAHLFGY RPYDKNISPR ENILVSLGAV 300
GEGFHNYHHS FPYDYSASEY RWHINFTTFF IDCMAALGLA YDRKKVSKAA ILARIKRTGD 360
GNYKSG 366 
Gene Ontology
 GO:0005783; C:endoplasmic reticulum; IEA:InterPro.
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0005506; F:iron ion binding; IEA:InterPro.
 GO:0004768; F:stearoyl-CoA 9-desaturase activity; IEA:InterPro.
 GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW. 
Interpro
 IPR005804; Fatty_acid_desaturase-1.
 IPR001522; Fatty_acid_desaturase-1_C.
 IPR015876; Fatty_acid_desaturase-1_core. 
Pfam
 PF00487; FA_desaturase 
SMART
  
PROSITE
 PS00476; FATTY_ACID_DESATUR_1 
PRINTS
 PR00075; FACDDSATRASE.