CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-032183
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Embigin 
Protein Synonyms/Alias
 Embigin homolog (Mouse), isoform CRA_c; cDNA FLJ50040, highly similar to Embigin 
Gene Name
 EMB 
Gene Synonyms/Alias
 hCG_2002649 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
55AVNVTWKKDGEQLENubiquitination[1]
85RFTIINSKQMGSYSCubiquitination[1]
107QRGTFNFKVPELHGKubiquitination[1]
116PELHGKNKPLISYVGubiquitination[1]
246KKHSDEGKEFEQIEQubiquitination[2]
255FEQIEQLKSDDSNGIubiquitination[2, 3]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [3] Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization.
 Sarraf SA, Raman M, Guarani-Pereira V, Sowa ME, Huttlin EL, Gygi SP, Harper JW.
 Nature. 2013 Apr 18;496(7445):372-6. [PMID: 23503661
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 277 AA 
Protein Sequence
MANNFSLESH NISLTEHSSM PVEKNITLER PSNVNLTCQF TTSGDLNAVN VTWKKDGEQL 60
ENNYLVSATG STLYTQYRFT IINSKQMGSY SCFFREEKEQ RGTFNFKVPE LHGKNKPLIS 120
YVGDSTVLTC KCQNCFPLNW TWYSSNGSVK VPVGVQMNKY VINGTYANET KLKITQLLEE 180
DGESYWCRAL FQLGESEEHI ELVVLSYLVP LKPFLVIVAE VILLVATILL CEKYTQKKKK 240
HSDEGKEFEQ IEQLKSDDSN GIENNVPRHR KNESLGQ 277 
Gene Ontology
 GO:0007155; P:cell adhesion; IEA:Compara. 
Interpro
 IPR027114; Embigin.
 IPR007110; Ig-like_dom.
 IPR013783; Ig-like_fold.
 IPR013098; Ig_I-set.
 IPR003599; Ig_sub. 
Pfam
 PF07679; I-set 
SMART
 SM00409; IG 
PROSITE
 PS50835; IG_LIKE 
PRINTS