CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-043883
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Insulin-like peptide INSL6 
Protein Synonyms/Alias
  
Gene Name
 RIF1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
602LIRAKNIKTIGDLSTubiquitination[1, 2]
616TLTASEIKTLPIRSPubiquitination[3]
641IYHEQQVKTRGLEEImethylation[4]
Reference
 [1] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473]
 [2] hCKSAAP_UbSite: improved prediction of human ubiquitination sites by exploiting amino acid pattern and properties.
 Chen Z, Zhou Y, Song J, Zhang Z.
 Biochim Biophys Acta. 2013 Aug;1834(8):1461-7. [PMID: 23603789]
 [3] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [4] Large-scale global identification of protein lysine methylation in vivo.
 Cao XJ, Arnaudo AM, Garcia BA.
 Epigenetics. 2013 May 1;8(5):477-85. [PMID: 23644510
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 746 AA 
Protein Sequence
XRSKGCDCCG EKSQPQEKSL IGLKNTENND VEISETKKAD VQAPVSPSET SQANPYSEGQ 60
FLDEHHSVNF HLGLKEDNDT INDSLIVSET KSKENTMQES LPSGIVNFRE EICDMDSSEA 120
MSLESQESPN ENFKTVGPCL GDSKNVSQES LETKEEKPEE TPKMELSLEN VTVEGNACKV 180
TESNLEKAKT MELNVGNEAS FHGQERTKTG ISEEAAIEEN KRNDDSEADT AKLNAKEVAT 240
EEFNSDISLS DNTTPVKLNA QTEISEQTAA GELDGGNDVS DLHSSEETNT KMKNNEEMMI 300
GEAMAETGHD GETENEGITT KTSKPDEAET NMLTAEMDNF VCDTVEMSTE EGIIDANKTE 360
TNTEYSKSEE KLDNNQMVME SDILQEDHHT SQKVEEPSQC LASGTAISEL IIEDNNASPQ 420
KLRELDPSLV SANDSPSGMQ TRCVWSPLAS PSTSILKRGL KRSQEDEISS PVNKVRRVSF 480
ADPIYQAGLA DDIDRRCSIV RSHSSNSSPI GKSVKTSPTT QSKHNTTSAK GFLSPGSRSP 540
KFKSSKKCLI SEMAKESIPC PTESVYPPLV NCVAPVDIIL PQITSNMWAR GLGQLIRAKN 600
IKTIGDLSTL TASEIKTLPI RSPKVSNVKK ALRIYHEQQV KTRGLEEIPV FDISEKTVNG 660
IENKSLSPDE ERLVSDIIDP VALEIPLSKN LLAQISALAL QLDSEDLHNY SGSQLFEMHE 720
KLSCMANSVI KNLQSRWRSP SHENSI 746 
Gene Ontology
  
Interpro
  
Pfam
  
SMART
  
PROSITE
  
PRINTS