CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-031675
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Histone-lysine N-methyltransferase SUV420H1 
Protein Synonyms/Alias
  
Gene Name
 SUV420H1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
20NGRRNGGKLSNDHQQacetylation[1]
37SKLQHTGKDTLKAGKacetylation[1]
Reference
 [1] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 402 AA 
Protein Sequence
MKWLGESKIM VVNGRRNGGK LSNDHQQNQS KLQHTGKDTL KAGKNAVERR SNRCNGNSGF 60
EGQSRYVPSS GMSAKELCEN DDLATSLVLD PYLGFQTHKM NTSAFPSRSS RHFSKSDSFS 120
HNNPVRFRPI KGRQEELKEV IERFKKDEHL EKAFKCLTSG EWARHYFLNK NKMQEKLFKE 180
HVFIYLRMFA TDSGFEILPC NRYSSEQNGA KIVATKEWKR NDKIELLVGC IAELSEIEEN 240
MLLRHGENDF SVMYSTRKNC AQLWLGPAAF INHDCRPNCK FVSTGRDTAC VKALRDIEPG 300
EEISCYYGDG FFGENNEFCE CYTCERRGTG AFKSRVGLPA PAPVINSKYG LRETDKRLNR 360
LKKLGDSSKN SDSQSVSSNT DADTTQEKNN AKNPEEKGRC FP 402 
Gene Ontology
 GO:0042799; F:histone methyltransferase activity (H4-K20 specific); IEA:InterPro.
 GO:0034773; P:histone H4-K20 trimethylation; IEA:InterPro. 
Interpro
 IPR025790; Hist-Lys_N-MTase_Suvar4-20.
 IPR001214; SET_dom. 
Pfam
 PF00856; SET 
SMART
 SM00317; SET 
PROSITE
 PS51570; SAM_MT43_SUVAR420_2
 PS50280; SET 
PRINTS