CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-024926
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 ATP-binding cassette, sub-family G (WHITE), member 1 
Protein Synonyms/Alias
 ATP-binding cassette, sub-family G (WHITE), member 1, isoform CRA_b 
Gene Name
 Abcg1 
Gene Synonyms/Alias
 mCG_14574 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
102KGYKTLLKGISGKFNubiquitination[1]
140GYRETGMKGAVLINGubiquitination[1]
354GMCDADYKRDLGGDTubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
  
Keyword
 ATP-binding; Nucleotide-binding. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 666 AA 
Protein Sequence
MACLMAAFSV GTAMNASSYS AAMTEPKSVC VSVDEVVSSN VDEVETDLLN GHLKKVDNNF 60
TEAQRFSSLP RRAAVNIEFK DLSYSVPEGP WWKKKGYKTL LKGISGKFNS GELVAIMGPS 120
GAGKSTLMNI LAGYRETGMK GAVLINGMPR DLRCFRKVSC YIMQDDMLLP HLTVQEAMMV 180
SAHLKLQEKD EGRREMVKEI LTALGLLPCA NTRTGSLSGG QRKRLAIALE LVNNPPVMFF 240
DEPTSGLDSA SCFQVVSLMK GLAQGGRSIV CTIHQPSAKL FELFDQLYVL SQGQCVYRGK 300
VSNLVPYLRD LGLNCPTYHN PADFVMEVAS GEYGDQNSRL VRAVREGMCD ADYKRDLGGD 360
TDVNPFLWHR PAEEDSASME GCHSFSASCL TQFCILFKRT FLSIMRDSVL THLRITSHIG 420
IGLLIGLLYL GIGNEAKKVL SNSGFLFFSM LFLMFAALMP TVLTFPLEMS VFLREHLNYW 480
YSLKAYYLAK TMADVPFQIM FPVAYCSIVY WMTSQPSDAV RFVLFAALGT MTSLVAQSLG 540
LLIGAASTSL QVATFVGPVT AIPVLLFSGF FVSFDTIPAY LQWMSYISYV RYGFEGVILS 600
IYGLDREDLH CDIAETCHFQ KSEAILRELD VENAKLYLDF IVLGIFFISL RLIAYFVLRY 660
KIRAER 666 
Gene Ontology
 GO:0009897; C:external side of plasma membrane; IEA:Compara.
 GO:0005794; C:Golgi apparatus; IEA:Compara.
 GO:0016021; C:integral to membrane; IEA:InterPro.
 GO:0005739; C:mitochondrion; IEA:Compara.
 GO:0043531; F:ADP binding; IEA:Compara.
 GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
 GO:0017127; F:cholesterol transporter activity; IEA:Compara.
 GO:0034437; F:glycoprotein transporter activity; IEA:Compara.
 GO:0005548; F:phospholipid transporter activity; IEA:Compara.
 GO:0034041; F:sterol-transporting ATPase activity; IEA:Compara.
 GO:0019534; F:toxin transporter activity; IEA:Compara.
 GO:0042987; P:amyloid precursor protein catabolic process; IEA:Compara.
 GO:0006200; P:ATP catabolic process; IEA:GOC.
 GO:0033344; P:cholesterol efflux; IEA:Compara.
 GO:0042632; P:cholesterol homeostasis; IEA:Compara.
 GO:0008203; P:cholesterol metabolic process; IEA:Compara.
 GO:0030301; P:cholesterol transport; IDA:MGI.
 GO:0034436; P:glycoprotein transport; IEA:Compara.
 GO:0032367; P:intracellular cholesterol transport; IEA:Compara.
 GO:0033700; P:phospholipid efflux; IEA:Compara.
 GO:0055091; P:phospholipid homeostasis; IEA:Compara.
 GO:0033993; P:response to lipid; IEA:Compara.
 GO:1901998; P:toxin transport; IEA:GOC. 
Interpro
 IPR003593; AAA+_ATPase.
 IPR013525; ABC_2_trans.
 IPR003439; ABC_transporter-like.
 IPR017871; ABC_transporter_CS.
 IPR020064; ABC_transptr_G1-like.
 IPR027417; P-loop_NTPase.
 IPR005284; Pigment_permease. 
Pfam
 PF01061; ABC2_membrane
 PF00005; ABC_tran 
SMART
 SM00382; AAA 
PROSITE
 PS00211; ABC_TRANSPORTER_1
 PS50893; ABC_TRANSPORTER_2 
PRINTS