CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-035423
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Protein Mki67 
Protein Synonyms/Alias
  
Gene Name
 Mki67 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
1225EEPSTLGKRTKSSDTacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 3164 AA 
Protein Sequence
MASSARLVTI KRSGDDGAHF PLSLSSCLFG RSIECDIRIQ LPVVSKKHCK IEVKEQEAIL 60
YNFSSANPTQ VNGTIINEPV QLKHGDIITI IDRSFRYEDG SHDGSRPTEF PRKSLGKEPA 120
RRASRDTISA DPDGKDQDTK ASKMTASRRS FVYAKGLSAD SPASDDSKDS VTQDSSGHVE 180
QHDRRNLGEP TSGDLFKKFR ATRSSYGDLK SSPAQSLSNS NKNESPFEKL YQSMKEELDV 240
KSEKSHRKSE PQFDRAAEES WETERLVSCK ARPKSSRSTP VTATSSPKVG KSWTERWRGG 300
VGPVQTPTET AKMKTPVQKA QQLKDEDSRV PGRRNSVNLD ESESAQAVHK IVTPGKLVTR 360
NQAAVKVGHV ASPANTPEHS SSKKRRSIPA DMEVPCAETQ KRLSLTQCLA PGEKKSPKDS 420
FSKPEKLGTV AKQTCSGITG LSSIDISNCG DSINKSEGVP LKRRRVSFGG HLRPELFDEN 480
LPPNTPLKRG ETPTKRKSLG THSPAGLKKI IKERPPSPGK QESPGVTPPR TNDERRRSGR 540
TSLASSGSKF LYETDIPKKA GRKSGNLPAK RASISRSQHG ILQMICSKRR SGASEANLIV 600
AKSWADVVKL GVKQTQMKVV KHVPQKQTRK RQRRPSTPKK PTSSLHDQFT TGHANSPCTI 660
VIGRAQTEKA SMPARPYKML NNLMLNWKMD FSEDLSAGLT EMFKTPVKEK QQQMSDVGSI 720
LSDSENLSER QLQGTNSEDT PPPTASEILG EKVLLSTQNA AKQQSNKYSA SSTLRRQSIK 780
HENTVQTPKN VHNITQIEKK TPASETEPLK TASSMSKLRR SRELRHTLVK SKNEKTEAVL 840
AKSITGRHLR KTFQGQEVDQ QVQGSENSSQ RCEENSKLSE DSEKTSARRS SARKQKLTKD 900
LVGSQMVTQS ADCAEDLLSQ EQGTIQNLEE SMEHFETPDL KDEPIGDDET KVLCKSPQPK 960
TENLKASAKP RTSTSRRKVD RKEELSAVTK LIHMSGESRH TPKVLKLEHG DIKALRQSEN 1020
EMLAATVTGS KRPLEKAKEK AQPVEDLTGF EELFLSPVPG DKITKMPSKS PHTESVRTPA 1080
STKRLSTTGL SKVDVREEPA TLGKRTKSSG RVTGTPAPAQ EDNDTTTFME TPKQKLDFTG 1140
NSTGHKRRSQ ASKNRAQPLE DLDGFQELFQ TPAAARTPVT VDESAKVSLE SVQPQLVITS 1200
ASTKRLSKTG LSKVDVREEP STLGKRTKSS DTVTGTPAPV QEENNTMAFM QTPKQKLDFT 1260
GNSTGHKRRS RASKNRAQPL EDLDGFQELF QTPAAASDPV TVDESAKVSL ESVQPQLVIT 1320
PASTKRLSKT GLSKVDVREE PSTLGKRTKS SDTVTGTPAP VQEENNTTAF MQTPKQKLDF 1380
TGNSTGHKRR SRASKNRAQP LEDLDGFQEL FQTPAAASDP VTVDESAKVS LESVQPQLVI 1440
TPASTKRLSK TGLSKVDVRE EPSTLGKRTK SSDTVTGTPA PVQDENNTTA FMQTPKQKLD 1500
FTGNSTGHKR RSRASKNRAQ PLEDLDGFQE LFQTPAAASD PVTVDESAKV SLESVQPQLV 1560
ITPASTKRLS KTGLSKVDVR EEPSTLGKRT KSSDTVTGTP APVQEENNTM AFMQTPKQKL 1620
DFTGNSTGHK RRSRASKNRA QPLEDLDGFQ ELFQTPAAAS DPVTVDESAK VSLESVQPQL 1680
VITPASTKRL SKTGLSKVDV REEPSTLGKR RKSSDTVTGT PAPVQDENNT MAFMQTPKQK 1740
LDFTGNSTGH KRRSRASKNR AQPLEDLDGF QELFQTPAAA SDPVTVDESA KVSLESVQPQ 1800
LVITPASTKR LSKTGLSKVD VREEPSTLGK RTKSSDTVTG TPAPVQDENN TTAFMQTPKQ 1860
KLDFTGNSTG HKRRSRASKN RAQPLEDLDG FQELFQTPAA ASDPVTVDES AKVSLESVQP 1920
QLVITPASTK RLSKTGLSKV DVREEPSTLG KRTKSSGRVT GTPAPVQEEN NTTTFMETPK 1980
QKLESLGDLT GLRKQSRTPK AKAQYLEDIS GFQEGFQTPD HANGPLAVGK TKKMSFISPQ 2040
PGSAITLKSI ERQSRASMSN MNVKEELLES EEHLQLGEGI DTLQVPNNNK VFRSSRKPAK 2100
RKLDPTASMP SSKRMRRSSK DSTPSLEDVT GSQQLCQMPG HAKDSLNTEA STMFTKPPQS 2160
GPVRTQNNRK SLPKISLRQV DVTGGISVLG KQSPGRALTA PVQADNGIKA IMETPKETLA 2220
TAADLTGFTR PQQTPKEKDQ PLEDYGGFQE LFQTPAGASD SVTVEESKKM PVESLQPQPV 2280
RTPASTKRLS KTGLSKVDVR EEPSTPGKRT KSSDTVTGTP APVPEENDTT PFMQTPKQKL 2340
EFTGNSAGHK RRSRTPKTRA QPLEDLDGFQ ELFQTPAGAS DPVTVDESTK VSLESSQPLP 2400
VITPASTKRL SKTPGRQLRT RLRNLYVKNE LSEDGMHPKM SGEIVDSSRA PGGEEKVIKA 2460
RKQCVKRKLD TAVNLPSSKR QRIAGAEEPQ TLEDLPGFQE LCQAPCLVMD SVIVDKTTKV 2520
PSKSPEPVDT TSEIKPRRRL KRLGVTEEPI PQRTTTRVLR QTRNTHKEPI DSSNGVDEFK 2580
ESSAQKQDPA ISLTGRRNQP RKVKEKTQPL EELTSFQEEI ATRMSCKSPQ PEEKKTLVGL 2640
KKQLRIQLFK VGVEEEPTAQ RKQPARETRS RLKEPMGNRI NVEELKKSTE QKIDPVASMT 2700
VSKRPRRIPK EKAQTVELAG LKGPIQTLGH TEESARDKEP TQMPCNSLQP EQVDSLQPSP 2760
RRPRTRHGKV EADKPSAVRK TVPTSRQSVR SRKVTEIDDN GTKASKAPVK QTLDTVAKET 2820
DSKRQLRTRK NGVQPLEVLG DSKEITQISD HSEKLRHDTN ILKSTLQQKP DSMKPLRKCR 2880
RVLRTSKEDP KEVLMDTSDL AALQSKSNLY LSPPRKSARD GRILKTRTLC SVTPKQEATG 2940
EKPVHKKQRA ASTKRQVSPE PVKVKHLRSV SHKRESVEEH ISTIMQIEEM EAKRENPVTP 3000
DQKIPQSSRY RKKTEKQPSP KFDASAEKVG IKKNEKTMKI SQETEPQNPD PGTKKSSSLG 3060
KVSGKRTCLR SRGQTEIPQP HEAEEKTRKS GAEISIKTQQ EKGVSGDPDV RRLRSRQTRV 3120
TLDNEPKPRV TRGAKKDAKT LKKDEDIVYT KILRTRSHQK SETV 3164 
Gene Ontology
 GO:0000775; C:chromosome, centromeric region; IEA:Compara.
 GO:0000793; C:condensed chromosome; IEA:Compara.
 GO:0005737; C:cytoplasm; IEA:Compara.
 GO:0005730; C:nucleolus; IEA:Compara.
 GO:0008283; P:cell proliferation; IEP:RGD.
 GO:0034605; P:cellular response to heat; IEP:RGD.
 GO:0006259; P:DNA metabolic process; IEP:RGD.
 GO:0030212; P:hyaluronan metabolic process; IEP:RGD.
 GO:0007126; P:meiosis; IEA:Compara.
 GO:0031100; P:organ regeneration; IEP:RGD.
 GO:0014070; P:response to organic cyclic compound; IEP:RGD. 
Interpro
 IPR000253; FHA_dom.
 IPR012568; K167R.
 IPR008984; SMAD_FHA_domain. 
Pfam
 PF00498; FHA
 PF08065; K167R 
SMART
 SM00240; FHA 
PROSITE
 PS50006; FHA_DOMAIN 
PRINTS