Tag | Content |
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CPLM ID | CPLM-008589 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | ER membrane protein complex subunit 4 |
Protein Synonyms/Alias | |
Gene Name | EMC4 |
Gene Synonyms/Alias | YGL231C |
Created Date | July 27, 2013 |
Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) |
NCBI Taxa ID | 559292 |
Lysine Modification | Position | Peptide | Type | References |
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48 | SKGNVTRKQQDATSQ | ubiquitination | [1] | 125 | FSTRSAFKPVLGNKA | ubiquitination | [1] |
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Reference | [1] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation. Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, Villén J. Nat Methods. 2013 Jul;10(7):676-82. [ PMID: 23749301] |
Functional Description | The EMC seems to be required for efficient folding of proteins in the endoplasmic reticulum (ER). |
Sequence Annotation | |
Keyword | Complete proteome; Endoplasmic reticulum; Membrane; Reference proteome; Transmembrane; Transmembrane helix. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 190 AA |
Protein Sequence | MSEQEPYEWA KHLLDTKYIE KYNIQNSNTL PSPPGFEGNS SKGNVTRKQQ DATSQTTSLA 60 QKNQITVLQV QKAWQIALQP AKSIPMNIFM SYMSGTSLQI IPIMTALMLL SGPIKAIFST 120 RSAFKPVLGN KATQSQVQTA MFMYIVFQGV LMYIGYRKLN SMGLIPNAKG DWLPWERIAH 180 YNNGLQWFSD 190 |
Gene Ontology | GO:0072546; C:ER membrane protein complex; IDA:SGD. GO:0034975; P:protein folding in endoplasmic reticulum; IGI:SGD. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |