CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-013509
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Kelch domain-containing protein 3 
Protein Synonyms/Alias
  
Gene Name
 KLHDC3 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Bos taurus (Bovine) 
NCBI Taxa ID
 9913 
Lysine Modification
Position
Peptide
Type
References
279NPVSFTWKKIEPKGKubiquitination[1]
280PVSFTWKKIEPKGKGubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961
Functional Description
 May be involved in meiotic recombination process (By similarity). 
Sequence Annotation
 REPEAT 25 77 Kelch 1.
 REPEAT 88 138 Kelch 2.
 REPEAT 139 189 Kelch 3.
 REPEAT 191 249 Kelch 4.
 REPEAT 251 301 Kelch 5.  
Keyword
 Alternative splicing; Complete proteome; Cytoplasm; Kelch repeat; Meiosis; Reference proteome; Repeat. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 382 AA 
Protein Sequence
MLRWTVHLEG GPRRVNHAAV AVGHRVYSFG GYCSGEDYET LRQIDVHIFN AVSLRWTKLP 60
PVRPAARGQA PVVPYMRYGH STVLIDDTVF LWGGRNDTEG ACNVLYAFDV NTHKWSTPRV 120
SGTVPGARDG HSACVLGKTM YIFGGYEQLA DCFSNDIHKL DTSTMTWTLI CTKGNPARWR 180
DFHSATMLGS HMYVFGGRAD RFGPFHSNNE IYCNRIRVFD TRTEAWLDCP PTPVLPEGRR 240
SHSAFGYNGE LYIFGGYNAR LNRHFHDLWK FNPVSFTWKK IEPKGKGPCP RRRQCCCIVG 300
DKIVLFGGTS PSPEEGLGDE FDLIDHSDLH ILDFSPSLKT LCKLAVIQYN LDQSCLPHDI 360
RWELNAMTTN SNISRPIVSS HG 382 
Gene Ontology
 GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
 GO:0007126; P:meiosis; IEA:UniProtKB-KW. 
Interpro
 IPR015915; Kelch-typ_b-propeller.
 IPR011498; Kelch_2. 
Pfam
 PF07646; Kelch_2 
SMART
  
PROSITE
  
PRINTS