CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-015093
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Uncharacterized protein C3orf17 
Protein Synonyms/Alias
  
Gene Name
 C3orf17 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
257GINKLLNKLFLINEQubiquitination[1, 2, 3, 4]
298VDLGQPVKNKRVFKEubiquitination[5]
300LGQPVKNKRVFKEESubiquitination[3]
320RAFCNQLKHKATQETubiquitination[3]
Reference
 [1] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473]
 [2] Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass.
 Povlsen LK, Beli P, Wagner SA, Poulsen SL, Sylvestersen KB, Poulsen JW, Nielsen ML, Bekker-Jensen S, Mailand N, Choudhary C.
 Nat Cell Biol. 2012 Oct;14(10):1089-98. [PMID: 23000965]
 [3] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [4] hCKSAAP_UbSite: improved prediction of human ubiquitination sites by exploiting amino acid pattern and properties.
 Chen Z, Zhou Y, Song J, Zhang Z.
 Biochim Biophys Acta. 2013 Aug;1834(8):1461-7. [PMID: 23603789]
 [5] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983
Functional Description
  
Sequence Annotation
 MOD_RES 265 265 Phosphoserine.  
Keyword
 Alternative splicing; Complete proteome; Membrane; Phosphoprotein; Polymorphism; Reference proteome; Transmembrane; Transmembrane helix. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 567 AA 
Protein Sequence
MMAAVPPGLE PWNRVRIPKA GNRSAVTVQN PGAALDLCIA AVIKECHLVI LSLKSQTLDA 60
ETDVLCAVLY SNHNRMGRHK PHLALKQVEQ CLKRLKNMNL EGSIQDLFEL FSSNENQPLT 120
TKVCVVPSQP VVELVLMKVL GACKLLLRLL DCCCKTFLLT VKHLGLQEFI ILNLVMVGLV 180
SRLWVLYKGV LKRLILLYEP LFGLLQEVAR IQPMPYFKDF TFPSDITEFL GQPYFEAFKK 240
KMPIAFAAKG INKLLNKLFL INEQSPRASE ETLLGISKKA KQMKINVQNN VDLGQPVKNK 300
RVFKEESSEF DVRAFCNQLK HKATQETSFD FKCSQSRLKT TKYSSQKVIG TPHAKSFVQR 360
FREAESFTQL SEEIQMAVVW CRSKKLKAQA IFLGNKLLKS NRLKHLEAQG TSLPKKLECI 420
KTSICNHLLR GSGIKTSKHH LRQRRSQNKF LRRQRKPQRK LQSTLLREIQ QFSQGTRKSA 480
TDTSAKWRLS HCTVHRTDLY PNSKQLLNSG VSMPVIQTKE KMIHENLRGI HENETDSWTV 540
MQINKNSTSG TIKETDDIDD IFALMGV 567 
Gene Ontology
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. 
Interpro
  
Pfam
  
SMART
  
PROSITE
  
PRINTS