CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-020998
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Probable methyltransferase-like protein 15 
Protein Synonyms/Alias
 Methyltransferase 5 domain-containing protein 1 
Gene Name
 Mettl15 
Gene Synonyms/Alias
 Mett5d1 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
230LRAYGEEKHAKKIASacetylation[1]
Reference
 [1] Calorie restriction and SIRT3 trigger global reprogramming of the mitochondrial protein acetylome.
 Hebert AS, Dittenhafer-Reed KE, Yu W, Bailey DJ, Selen ES, Boersma MD, Carson JJ, Tonelli M, Balloon AJ, Higbee AJ, Westphall MS, Pagliarini DJ, Prolla TA, Assadi-Porter F, Roy S, Denu JM, Coon JJ.
 Mol Cell. 2013 Jan 10;49(1):186-99. [PMID: 23201123] 
Functional Description
 Probable S-adenosyl-L-methionine-dependent methyltransferase (By similarity). 
Sequence Annotation
 REGION 100 102 S-adenosyl-L-methionine binding (By
 BINDING 119 119 S-adenosyl-L-methionine (By similarity).
 BINDING 146 146 S-adenosyl-L-methionine; via amide
 BINDING 169 169 S-adenosyl-L-methionine (By similarity).
 BINDING 176 176 S-adenosyl-L-methionine (By similarity).  
Keyword
 Complete proteome; Methyltransferase; Reference proteome; S-adenosyl-L-methionine; Transferase. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 406 AA 
Protein Sequence
MLRYPYFYRT YNRLFSHFVD SGASNLDVCP HTIHTAVALH TESKAVEGTA LCGPQKVYSS 60
EEKELEAMAK LHIPVMVDQV VHCLAPQKGQ VFLDMTFGSG GHTRAILQKE PDVMVYALDR 120
DPVAYAIAEQ LSRLYPTQIQ ALLGQFSQAE ALLMKAGVQP GTIDGILMDL GCSSMQLDAP 180
ERGFSLRKDG PLDMRMDGDR YPDTPTASDV VNALDQQALA SILRAYGEEK HAKKIASAII 240
QARSTYPISR TQQLASIVAG AFPPSAVYAR KDLLQRSTHI ATKTFQALRI FVNNELNELY 300
AGLRTAEKFL KTGGRLVALS FHSLEDRIVK RFLLGISMTE RFNLSIRQKV KQTSQLDSDQ 360
ETEERHSVRA PLKWELIHKK VLTPEDQDVQ DNPRGRSAKL RAAIKL 406 
Gene Ontology
 GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW. 
Interpro
 IPR002903; RsmH.
 IPR023397; SAM-dep_MeTrfase_MraW_recog. 
Pfam
 PF01795; Methyltransf_5 
SMART
  
PROSITE
  
PRINTS