CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-021090
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Ataxin-10 
Protein Synonyms/Alias
 Neuronal beta-catenin-like protein; Spinocerebellar ataxia type 10 protein homolog 
Gene Name
 Atxn10 
Gene Synonyms/Alias
 Sca10 
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
262VGDEQLTKDDISIFLubiquitination[1]
Reference
 [1] Synaptic protein ubiquitination in rat brain revealed by antibody-based ubiquitome analysis.
 Na CH, Jones DR, Yang Y, Wang X, Xu Y, Peng J.
 J Proteome Res. 2012 Sep 7;11(9):4722-32. [PMID: 22871113
Functional Description
 Necessary for the survival of cerebellar neurons. Induces neuritogenesis by activating the Ras-MAP kinase pathway. May play a role in the maintenance of a critical intracellular glycosylation level and homeostasis. 
Sequence Annotation
 MOD_RES 12 12 Phosphoserine (By similarity).  
Keyword
 Complete proteome; Cytoplasm; Phosphoprotein; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 475 AA 
Protein Sequence
MAAPRMPPSR LSGIMVPAPI QDLEALRALT ALFKEQRNRE TAPRTIFQRV LDILKKSTQA 60
VELACRDPSQ VEHLASSLQL ITECFRCLRN ACIECSVNQN SIRNLDTIGV AVDLVLLFRE 120
LRVEQDSLLT AFRCGLQFLG NVASRNEDSQ SIVWVHAFPE LFMSCLNHPD KKIVAYCSMI 180
LFTSLNSERM KDLEENLNIA INVIEAHQKH PESEWPFLII TDHFLKSPEL VEAMYGKLSN 240
QERVTLLDIM IAKIVGDEQL TKDDISIFLR HAELIANSFV DQCRNVLKLT SEPQTEDKEA 300
LVTIRLLDVL CEMTSNTELL GYLQVFPGLM ERVIDVLRVI HSVGKDSTNI FSPSDSLKAE 360
GDIEHMTEGF KSHLIRLIGN LCYKNKENQD KVNELDGIPL ILDSSNIDDN NPFMMQWVVY 420
AVRNLTEDNS QNQDFIAKME EQGLADASLL KKMGFEVEKS GDKLILKSNN DIPPP 475 
Gene Ontology
 GO:0005829; C:cytosol; IDA:RGD.
 GO:0030425; C:dendrite; IEA:Compara.
 GO:0043025; C:neuronal cell body; IEA:Compara.
 GO:0048471; C:perinuclear region of cytoplasm; ISS:UniProtKB.
 GO:0042802; F:identical protein binding; IDA:RGD.
 GO:0031175; P:neuron projection development; ISS:UniProtKB. 
Interpro
 IPR011989; ARM-like.
 IPR016024; ARM-type_fold.
 IPR019156; Ataxin-10_domain. 
Pfam
 PF09759; Atx10homo_assoc 
SMART
  
PROSITE
  
PRINTS