| Tag | Content |
|---|
| CPLM ID | CPLM-007905 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | GPI mannosyltransferase 1 |
Protein Synonyms/Alias | GPI mannosyltransferase I; GPI-MT-I; Glycosylphosphatidylinositol-anchor biosynthesis protein 14 |
Gene Name | GPI14 |
Gene Synonyms/Alias | PMH1; YJR013W; J1444; YJR83.11 |
Created Date | July 27, 2013 |
Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) |
NCBI Taxa ID | 559292 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 53 | AKYVYEGKSPYARDT | ubiquitination | [1] |
|
Reference | [1] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation. Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, Villén J. Nat Methods. 2013 Jul;10(7):676-82. [ PMID: 23749301] |
Functional Description | Mannosyltransferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers the first alpha-1,4-mannose to GlcN-acyl-PI during GPI precursor assembly. Required for cell wall integrity. |
Sequence Annotation | |
Keyword | Cell wall biogenesis/degradation; Complete proteome; Endoplasmic reticulum; Glycosyltransferase; GPI-anchor biosynthesis; Membrane; Reference proteome; Transferase; Transmembrane; Transmembrane helix. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 403 AA |
Protein Sequence | MTGEEWGLTV LSFLVRVGFF LFGIYQDANF KVRYTDIDYF VFHDAAKYVY EGKSPYARDT 60
YRYTPLLSWL LVPNHYFGWF HLGKVIFVIF DLVTGLIIMK LLNQAISRKR ALILESIWLL 120
NPMVITISTR GNAESVLCCL IMFTLFFLQK SRYTLAGILY GLSIHFKIYP IIYCIPIAIF 180
IYYNKRNQGP RTQLTSLLNI GLSTLTTLLG CGWAMYKIYG YEFLDQAYLY HLYRTDHRHN 240
FSVWNMLLYL DSANKENGES NLSRYAFVPQ LLLVLVTGCL EWWNPTFDNL LRVLFVQTFA 300
FVTYNKVCTS QYFVWYLIFL PFYLSRTHIG WKKGLLMATL WVGTQGIWLS QGYYLEFEGK 360
NVFYPGLFIA SVLFFVTNVW LLGQFITDIK IPTQPTVSNK KNN 403 |
Gene Ontology | GO:0005789; C:endoplasmic reticulum membrane; ISS:SGD. GO:0016021; C:integral to membrane; ISM:SGD. GO:0000030; F:mannosyltransferase activity; ISS:SGD. GO:0031505; P:fungal-type cell wall organization; IMP:SGD. GO:0006506; P:GPI anchor biosynthetic process; IMP:SGD. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |