CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-014729
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Protein sel-1 homolog 3 
Protein Synonyms/Alias
 Suppressor of lin-12-like protein 3; Sel-1L3 
Gene Name
 SEL1L3 
Gene Synonyms/Alias
 KIAA0746 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
438IFNPLLEKQLAEQIKubiquitination[1, 2]
Reference
 [1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [2] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 
Functional Description
  
Sequence Annotation
 REPEAT 575 609 Sel1-like 1.
 REPEAT 611 647 Sel1-like 2.
 REPEAT 694 730 Sel1-like 3.
 REPEAT 732 767 Sel1-like 4.
 REPEAT 768 800 Sel1-like 5.
 REPEAT 801 839 Sel1-like 6.
 REPEAT 840 877 Sel1-like 7.
 REPEAT 952 988 Sel1-like 8.
 MOD_RES 608 608 Phosphoserine.
 CARBOHYD 201 201 N-linked (GlcNAc...) (Potential).
 CARBOHYD 382 382 N-linked (GlcNAc...) (Potential).
 CARBOHYD 527 527 N-linked (GlcNAc...) (Potential).
 CARBOHYD 937 937 N-linked (GlcNAc...) (Potential).  
Keyword
 Alternative splicing; Complete proteome; Glycoprotein; Membrane; Phosphoprotein; Polymorphism; Reference proteome; Repeat; Transmembrane; Transmembrane helix. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1132 AA 
Protein Sequence
MQRRGAGLGW PRQQQQQPPP LAVGPRAAAM VPSGGVPQGL GGRSACALLL LCYLNVVPSL 60
GRQTSLTTSV IPKAEQSVAY KDFIYFTVFE GNVRNVSEVS VEYLCSQPCV VNLEAVVSSE 120
FRSSIPVYKK RWKNEKHLHT SRTQIVHVKF PSIMVYRDDY FIRHSISVSA VIVRAWITHK 180
YSGRDWNVKW EENLLHAVAK NYTLLQTIPP FERPFKDHQV CLEWNMGYIW NLRANRIPQC 240
PLENDVVALL GFPYASSGEN TGIVKKFPRF RNRELEATRR QRMDYPVFTV SLWLYLLHYC 300
KANLCGILYF VDSNEMYGTP SVFLTEEGYL HIQMHLVKGE DLAVKTKFII PLKEWFRLDI 360
SFNGGQIVVT TSIGQDLKSY HNQTISFRED FHYNDTAGYF IIGGSRYVAG IEGFFGPLKY 420
YRLRSLHPAQ IFNPLLEKQL AEQIKLYYER CAEVQEIVSV YASAAKHGGE RQEACHLHNS 480
YLDLQRRYGR PSMCRAFPWE KELKDKHPSL FQALLEMDLL TVPRNQNESV SEIGGKIFEK 540
AVKRLSSIDG LHQISSIVPF LTDSSCCGYH KASYYLAVFY ETGLNVPRDQ LQGMLYSLVG 600
GQGSERLSSM NLGYKHYQGI DNYPLDWELS YAYYSNIATK TPLDQHTLQG DQAYVETIRL 660
KDDEILKVQT KEDGDVFMWL KHEATRGNAA AQQRLAQMLF WGQQGVAKNP EAAIEWYAKG 720
ALETEDPALI YDYAIVLFKG QGVKKNRRLA LELMKKAASK GLHQAVNGLG WYYHKFKKNY 780
AKAAKYWLKA EEMGNPDASY NLGVLHLDGI FPGVPGRNQT LAGEYFHKAA QGGHMEGTLW 840
CSLYYITGNL ETFPRDPEKA VVWAKHVAEK NGYLGHVIRK GLNAYLEGSW HEALLYYVLA 900
AETGIEVSQT NLAHICEERP DLARRYLGVN CVWRYYNFSV FQIDAPSFAY LKMGDLYYYG 960
HQNQSQDLEL SVQMYAQAAL DGDSQGFFNL ALLIEEGTII PHHILDFLEI DSTLHSNNIS 1020
ILQELYERCW SHSNEESFSP CSLAWLYLHL RLLWGAILHS ALIYFLGTFL LSILIAWTVQ 1080
YFQSVSASDP PPRPSQASPD TATSTASPAV TPAADASDQD QPTVTNNPEP RG 1132 
Gene Ontology
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. 
Interpro
 IPR006597; Sel1-like.
 IPR011990; TPR-like_helical. 
Pfam
 PF08238; Sel1 
SMART
 SM00671; SEL1 
PROSITE
  
PRINTS