| Tag | Content |
|---|
| CPLM ID | CPLM-016001 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Sodium-dependent phosphate transport protein 2C |
Protein Synonyms/Alias | Sodium-phosphate transport protein 2C; Na(+)-dependent phosphate cotransporter 2C; Sodium/phosphate cotransporter 2C; Na(+)/Pi cotransporter 2C; NaPi-2c; Solute carrier family 34 member 3 |
Gene Name | Slc34a3 |
Gene Synonyms/Alias | Npt2c |
Created Date | July 27, 2013 |
Organism | Mus musculus (Mouse) |
NCBI Taxa ID | 10090 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 57 | LKNADQLKEVGMASR | ubiquitination | [1] |
|
Reference | [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues. Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C. Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [ PMID: 22790023] |
Functional Description | May be involved in actively transporting phosphate into cells via Na(+) cotransport in the renal brush border membrane. Probably mediates 20-30% of the apical influx. |
Sequence Annotation | CARBOHYD 264 264 N-linked (GlcNAc...) (Potential).
CARBOHYD 267 267 N-linked (GlcNAc...) (Potential).
CARBOHYD 299 299 N-linked (GlcNAc...) (Potential).
DISULFID 275 311 By similarity. |
Keyword | Complete proteome; Disulfide bond; Glycoprotein; Ion transport; Membrane; Reference proteome; Sodium; Sodium transport; Symport; Transmembrane; Transmembrane helix; Transport. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 601 AA |
Protein Sequence | MPNSLAGGQV PNPTLDAFDL VDRSLRNAGI SGSIPGLEEG GTDPWTFSPL KNADQLKEVG 60
MASRLRRVVS SFLKACGLLG SLYFFICSLD ILSSAFQLLG SKMAGDIFKD NVVLSNPVAG 120
LVIGVLVTVL VQSSSTSSSI VVSMVASKLL TVQVSVPIIM GVNVGTSITS TLVSMAQSGD 180
RDEFQRAFSG SAVHGIFNWL TVLVLLPLES ATAALERLSE LALGAASLQP GQQAPDILKA 240
LTRPFTHLII QLDSSVITSG ITSNTTNSSL IKHWCGFRGE TPQGSSEGCG LFSSCTERNS 300
SASPEEDRLL CHHLFAGSKL TDLAVGFILL AGSLLVLCVC LVLIVKLLNS VLKGRIAQAV 360
KTVINADFPF PFGWLSGYLA ILVGAGLTFL LQSSSVFTAA IVPLMGVGVI DLERAYPLFL 420
GSNIGTTTTA LLAALASPAD MLIFAVQVAL IHFFFNLAGI LLWYLVPVLR LPIPLAKRFG 480
NLTAQYRWVA IVYLLLTFLL LPLAAFGLSL AGGTVLAAVG GPLVGLVLLI ILVNVLQQHR 540
PSWLPRCLQS WAWLPLWLHS LEPWDRLVTA CCPCRACSNS PMTSKVAHCY ENPQVIASQQ 600
L 601 |
Gene Ontology | GO:0016324; C:apical plasma membrane; IDA:MGI. GO:0005903; C:brush border; IDA:MGI. GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. GO:0015321; F:sodium-dependent phosphate transmembrane transporter activity; IDA:MGI. GO:0005436; F:sodium:phosphate symporter activity; IEA:Compara. GO:0030643; P:cellular phosphate ion homeostasis; IEA:Compara. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |