CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-012827
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Cytospin-A 
Protein Synonyms/Alias
 SPECC1-like protein; Sperm antigen with calponin homology and coiled-coil domains 1-like 
Gene Name
 Specc1l 
Gene Synonyms/Alias
 Cytsa 
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
726VKKLQDQKHDLERENacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
 Involved in cytokinesis and spindle organization. May play a role in actin cytoskeleton organization and microtubule stabilization and hence required for proper cell adhesion and migration (By similarity). 
Sequence Annotation
 DOMAIN 1012 1114 CH.
 MOD_RES 54 54 Phosphoserine (By similarity).
 MOD_RES 869 869 Phosphoserine (By similarity).
 MOD_RES 882 882 Phosphoserine (By similarity).
 MOD_RES 888 888 Phosphoserine (By similarity).  
Keyword
 Cell cycle; Cell division; Cell junction; Coiled coil; Complete proteome; Cytoplasm; Cytoskeleton; Gap junction; Phosphoprotein; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1118 AA 
Protein Sequence
MKKANRSAGS VPKVSGISKP QTVEKSKSEN SSSAPTGGKP VKPGAAAALS KTKSNDDLLA 60
GMAGGVNVTN GVKAKKSNCS SAAPSAPAPA MTISESKSKS STGTSSSAKR STSAGNKESS 120
STRERLRERT RLNQSKKLPS VSQGANDVAL AKRSRSRTAT EGDIRMSKSK SDNQISDKAA 180
LEAKVKDLLT LAKTKDVEIL HLRNELRDMR AQLGISEDHC EGEDRSEEKE TIIAHQPTDV 240
ESTLLQLQEQ NTAIREELNQ LKNENRMLKD RLNALGFSLE QRLDNSEKLF GYQSLSPEIT 300
PGNQSDGGGT LTSSVEGSAP GSVEDLLSQD ENTLMAHQHS NSMDNLDSEC SEVYQPLTSS 360
DDALDAPSSS ESEGVPSIER SRKGSSGNAS EVSVACLTER IHQMEENQHS TSEELQATLQ 420
ELADLQQITQ ELNSENERLG EEKVILMESL CQQSDKLEHF GRQIEYFRSL LDEHHISYVI 480
DEDVKSGRYM ELEQRYMDLA ENARFEREQL LGVQQHLSNT LKMAEQDNKE AQEMIGALKE 540
RSHHMERIIE SEQKGKAALA ATLEEYKATV ASDQIEMNRL KAQLEKEKQK VAELYSIHNS 600
GDKSDIQDLL ESVRLDKEKA ETLASSLQED LAHTRNDANR LQDTIAKVED EYRAFQEEAK 660
KQIEDLNMTL EKLRSELEEK ETERSDMKET IFELEDEVEQ HRAVKLHDNL IISDLENTVK 720
KLQDQKHDLE RENKTLHRRL REESAEWRQF QADLQTAVVI ANDIKSEAQE EIGDLKRRLH 780
EAQEKNEKLT KELEEIKSRK QEEERGRVYN YMNAVERDLA ALRQGMGLSR RSSTSSEPTP 840
TVKTLIKSFD SASQVPNAAA AAIPRTPLSP SPMKTPPAAA VSPMQRHSIS GPVSTSKPLT 900
ALSDKRSNYG EIPGQEHLLR TSSTSRPASL PRVPAMESAK TISVSRRSSE EMKRDISASE 960
GASPASLMAM GTTSPQLSLS SSPTASVTPS TRSRIREERK DPLSALAREY GGSKRNALLK 1020
WCQKKTEGYQ NIDITNFSSS WNDGLAFCAL LHTYLPAHIP YQELNSQEKK RNFTLAFQAA 1080
ESVGIKSTLD INEMARTERP DWQNVMLYVT AIYKYFET 1118 
Gene Ontology
 GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
 GO:0005921; C:gap junction; IEA:UniProtKB-SubCell.
 GO:0005819; C:spindle; IEA:UniProtKB-SubCell.
 GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
 GO:0051301; P:cell division; IEA:UniProtKB-KW. 
Interpro
 IPR001715; CH-domain. 
Pfam
 PF00307; CH 
SMART
 SM00033; CH 
PROSITE
 PS50021; CH 
PRINTS