| Tag | Content |
|---|
| CPLM ID | CPLM-014899 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Zinc finger protein 470 |
Protein Synonyms/Alias | Chondrogenesis zinc finger protein 1; CZF-1 |
Gene Name | ZNF470 |
Gene Synonyms/Alias | CZF1 |
Created Date | July 27, 2013 |
Organism | Homo sapiens (Human) |
NCBI Taxa ID | 9606 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 50 | AQRSLYKKVMLENYR | ubiquitination | [1] | | 479 | QRVHTGEKPYECKEC | ubiquitination | [1] |
|
Reference | [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments. Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA. Mol Cell Proteomics. 2013 Mar;12(3):825-31. [ PMID: 23266961] |
Functional Description | May be involved in transcriptional regulation. |
Sequence Annotation | DOMAIN 23 94 KRAB.
ZN_FING 228 250 C2H2-type 1.
ZN_FING 256 278 C2H2-type 2.
ZN_FING 284 306 C2H2-type 3.
ZN_FING 312 334 C2H2-type 4.
ZN_FING 340 362 C2H2-type 5.
ZN_FING 368 391 C2H2-type 6.
ZN_FING 397 419 C2H2-type 7.
ZN_FING 425 447 C2H2-type 8.
ZN_FING 453 475 C2H2-type 9.
ZN_FING 481 503 C2H2-type 10.
ZN_FING 509 531 C2H2-type 11.
ZN_FING 537 559 C2H2-type 12.
ZN_FING 565 587 C2H2-type 13.
ZN_FING 593 615 C2H2-type 14.
ZN_FING 621 643 C2H2-type 15.
ZN_FING 649 671 C2H2-type 16.
ZN_FING 677 699 C2H2-type 17.
MOTIF 216 219 Nuclear localization signal (Potential).
MOTIF 385 388 Nuclear localization signal (Potential). |
Keyword | Alternative splicing; Complete proteome; DNA-binding; Metal-binding; Nucleus; Polymorphism; Reference proteome; Repeat; Transcription; Transcription regulation; Zinc; Zinc-finger. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 717 AA |
Protein Sequence | MKSQEEVEVA GIKLCKAMSL GSVTFTDVAI DFSQDEWEWL NLAQRSLYKK VMLENYRNLV 60
SVGLCISKPD VISLLEQEKD PWVIKGGMNR GLCPDLECVW VTKSLSLNQD IYEEKLPPAI 120
IMERLKSYDL ECSTLGKNWK CEDLFERELV NQKTHFRQET ITHIDTLIEK RDHSNKSGTV 180
FHLNTLSYIK QIFPMEERIF NFHTDKKSLK THSVVKKHKQ DRGEKKLLKC NDCEKIFSKI 240
STLTLHQRIH TGEKPYECIE CGKAFSQSAH LAQHQRIHTG EKPFECTECG KAFSQNAHLV 300
QHQRVHTGEK PYQCKQCNKA FSQLAHLAQH QRVHTGEKPY ECIECGKAFS DCSSLAHHRR 360
IHTGKRPYEC IDCGKAFRQN ASLIRHRRYY HTGEKPFDCI DCGKAFTDHI GLIQHKRTHT 420
GERPYKCNVC GKAFSHGSSL TVHQRIHTGE KPYECNICEK AFSHRGSLTL HQRVHTGEKP 480
YECKECGKAF RQSTHLAHHQ RIHTGEKPYE CKECSKTFSQ NAHLAQHQKI HTGEKPYECK 540
ECGKAFSQIA HLVQHQRVHT GEKPYECIEC GKAFSDGSYL VQHQRLHSGK RPYECLECGK 600
AFRQRASLIC HQRCHTGEKP YECNVCGKAF SHRKSLTLHQ RIHTGEKPYE CKECSKAFSQ 660
VAHLTLHKRI HTGERPYECK ECGKAFRQSV HLAHHQRIHT GESSVILSSA LPYHQVL 717 |
Gene Ontology | GO:0005634; C:nucleus; IDA:HPA. GO:0003677; F:DNA binding; IEA:UniProtKB-KW. GO:0008270; F:zinc ion binding; IEA:InterPro. GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW. GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |