CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-011110
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Non-structural maintenance of chromosome element 5 
Protein Synonyms/Alias
 Non-SMC element 5 
Gene Name
 NSE5 
Gene Synonyms/Alias
 YML023C 
Created Date
 July 27, 2013 
Organism
 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 
NCBI Taxa ID
 559292 
Lysine Modification
Position
Peptide
Type
References
400NDILQFKKFFMTENLubiquitination[1]
Reference
 [1] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.
 Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, Villén J.
 Nat Methods. 2013 Jul;10(7):676-82. [PMID: 23749301] 
Functional Description
 Acts in a DNA repair pathway for removal of UV-induced DNA damage that is distinct from classical nucleotide excision repair and in repair of ionizing radiation damage. Functions in homologous recombination repair of DNA double strand breaks and in recovery of stalled replication forks. 
Sequence Annotation
  
Keyword
 Complete proteome; DNA damage; DNA recombination; DNA repair; Nucleus; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 556 AA 
Protein Sequence
MDGALINSVL YVSPRNGAHY FVELTEKHLL AFEMLNSMCL LENYDHVLLF LECQFGKSHN 60
LAVIPFDIIL VLFTLSTLSE YYKEPILRAN DPYNTSRETL SRRALKLLQK YLAILKEFDS 120
EQYNLYDLEL LRCQFFLAID TLTPKKQKWG FDRFRRTKSE SGVTYRQNAS VDPELDQAKT 180
FKNPYRSYIS CLEQRNTILG NRLLNLKLNE PGEFINMILW TLSNSLQEST PLFLSSHEIW 240
MPLLEILIDL FSCRQDYFIQ HEVAQNVSKS LFVQRLSESP LAVFFESLNT RNFANRFSEY 300
VFLNCDYKLP SDNYATPVHP VYNGENTIVD TYIPTIKCSP LYKSQKSLAL RRKLIGSCFK 360
LLLRVPDGHR LITPRIVADD VIQGISRTLA SFNDILQFKK FFMTENLSQE SYFIPLLAEG 420
TLSEILKDTQ ECVVILTLVE NLSDGVSFCN EVIGLVKSKC FAFTEQCSQA SYEEAVLNIE 480
KCDVCLLVLL RYLLHLIGTE AILDAKEQLE MLHAIEKNDS GRRQWAKALN LGNDPPLLYP 540
IVSQMFGVHD KSVIIE 556 
Gene Ontology
 GO:0005634; C:nucleus; IDA:SGD.
 GO:0030915; C:Smc5-Smc6 complex; IDA:SGD.
 GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.
 GO:0006281; P:DNA repair; IMP:SGD. 
Interpro
 IPR014803; DNA_repair_Nse5/Nse6. 
Pfam
 PF08691; Nse5 
SMART
  
PROSITE
  
PRINTS