CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-009119
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 NAD kinase 
Protein Synonyms/Alias
 Poly(P)/ATP NAD kinase 
Gene Name
 Nadk 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
57SPALGSTKEFRRTRSubiquitination[1]
102SQRLTWNKSPKSVLVubiquitination[1]
159DENFGPVKKKFCTFRubiquitination[1]
253VKEPRDKKTAIHNGLubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
 MOD_RES 46 46 Phosphoserine (By similarity).
 MOD_RES 48 48 Phosphoserine (By similarity).
 MOD_RES 50 50 Phosphoserine (By similarity).
 MOD_RES 64 64 Phosphoserine.  
Keyword
 ATP-binding; Complete proteome; Kinase; Metal-binding; NAD; NADP; Nucleotide-binding; Phosphoprotein; Reference proteome; Transferase. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 439 AA 
Protein Sequence
MEMEQEKMNL SQELSADSAS YNCSACHGDE TWSYNHPIRG RAKSRSLSAS PALGSTKEFR 60
RTRSLHGPCP VTTFGPKACV LQNPQTIMHI QDPASQRLTW NKSPKSVLVI KKIRDASLLQ 120
PFKELCIYLM EENNMIVYVE KKVLEDPAIV SDENFGPVKK KFCTFREDYD DISNQIDFII 180
CLGGDGTLLY ASSLFQGSVP PVMAFHLGSL GFLTPFNFEN FQSQVNQVIE GNAAVILRSR 240
LKVRVVKEPR DKKTAIHNGL SENGLDTEGG KQAMQYQVLN EVVIDRGPSS YLSNVDVYLD 300
GHLITTVQGD GVIVSTPTGS TAYAAAAGAS MVHPNVPAIM VTPICPHSLS FRPIVVPAGV 360
ELKIMLSPEA RNTAWVSFDG RKRQEIRHGD SISITTSCYP LPSICVCDPV SDWFESLAQC 420
LHWNVRKKQA HFPEDEEDS 439 
Gene Ontology
 GO:0005829; C:cytosol; ISS:UniProtKB.
 GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
 GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
 GO:0003951; F:NAD+ kinase activity; ISS:UniProtKB.
 GO:0019674; P:NAD metabolic process; IEA:InterPro.
 GO:0006741; P:NADP biosynthetic process; IEA:InterPro. 
Interpro
 IPR017438; ATP-NAD_kinase_dom_1.
 IPR016064; ATP-NAD_kinase_PpnK-typ.
 IPR017437; ATP-NAD_kinase_PpnK-typ_all-b.
 IPR002504; PolyP/ATP_NADK_prd. 
Pfam
 PF01513; NAD_kinase 
SMART
  
PROSITE
  
PRINTS