UniProt Accession

 H7C4L7_HUMAN; H7C4L7 

Genbank Protein ID

 AL096712 

Genbank Nucleotide ID

  

Protein Name

 E3 ubiquitin-protein ligase RNF8 

Protein Synonyms/Alias

  

Gene Name

 RNF8 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
74	TQKGNSKKVVQMEQE	ubiquitination	[1]
124	LEIAQGEKDLKQQLA	ubiquitination	[1]

Reference

 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 208 AA 

Protein Sequence

Gene Ontology

 GO:0005634; C:nucleus; IEA:InterPro.
 GO:0016881; F:acid-amino acid ligase activity; IEA:InterPro.
 GO:0051301; P:cell division; IEA:InterPro.
 GO:0016567; P:protein ubiquitination; IEA:InterPro.
 GO:0006974; P:response to DNA damage stimulus; IEA:InterPro. 

Interpro

 IPR017335; E3_Ub_ligase_RNF8. 

Pfam

  

SMART

  

PROSITE

  

PRINTS