| Tag | Content |
|---|
| CPLM ID | CPLM-010267 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Hydroxyethylthiazole kinase |
Protein Synonyms/Alias | 4-methyl-5-beta-hydroxyethylthiazole kinase; TH kinase; Thz kinase |
Gene Name | thiM |
Gene Synonyms/Alias | b2104; JW2091 |
Created Date | July 27, 2013 |
Organism | Escherichia coli (strain K12) |
NCBI Taxa ID | 83333 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 90 | RAAVEQAKSSQTPWT | acetylation | [1] | | 120 | CHELLSFKPAAIRGN | acetylation | [1] |
|
Reference | [1] Acetyl-Phosphate Is a Critical Determinant of Lysine Acetylation in E. coli. Weinert BT, Iesmantavicius V, Wagner SA, Schölz C, Gummesson B, Beli P, Nyström T, Choudhary C. Mol Cell. 2013 Jul 25;51(2):265-72. [ PMID: 23830618] |
Functional Description | |
Sequence Annotation | BINDING 50 50 Substrate; via amide nitrogen (By
BINDING 125 125 ATP (By similarity).
BINDING 171 171 ATP (By similarity).
BINDING 198 198 Substrate; via amide nitrogen (By |
Keyword | ATP-binding; Complete proteome; Kinase; Magnesium; Metal-binding; Nucleotide-binding; Reference proteome; Thiamine biosynthesis; Transferase. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 262 AA |
Protein Sequence | MQVDLLGSAQ SAHALHLFHQ HSPLVHCMTN DVVQTFTANT LLALGASPAM VIETEEASQF 60
AAIASALLIN VGTLTQPRAQ AMRAAVEQAK SSQTPWTLDP VAVGALDYRR HFCHELLSFK 120
PAAIRGNASE IMALAGIANG GRGVDTTDAA ANAIPAAQTL ARETGAIVVV TGEMDYVTDG 180
HRIIGIHGGD PLMTKVVGTG CALSAVVAAC CALPGDTLEN VASACHWMKQ AGERAVARSE 240
GPGSFVPHFL DALWQLTQEV QA 262 |
Gene Ontology | GO:0005524; F:ATP binding; IEA:HAMAP. GO:0004417; F:hydroxyethylthiazole kinase activity; IEA:HAMAP. GO:0000287; F:magnesium ion binding; IEA:HAMAP. GO:0009228; P:thiamine biosynthetic process; IEA:UniProtKB-KW. GO:0009229; P:thiamine diphosphate biosynthetic process; IEA:UniProtKB-UniPathway. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |