CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-022424
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Uncharacterized protein C9orf78 
Protein Synonyms/Alias
 Hepatocellular carcinoma-associated antigen 59 
Gene Name
 C9orf78 
Gene Synonyms/Alias
 HCA59 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
72VDDPFQMKTGGMVDMubiquitination[1]
125YIETELKKRKGIVEHubiquitination[1]
136IVEHEEQKVKPKNAEubiquitination[2]
138EHEEQKVKPKNAEDCubiquitination[1]
140EEQKVKPKNAEDCLYubiquitination[1]
185LGIDAKIKNIISTEDubiquitination[1, 2]
194IISTEDAKARLLAEQubiquitination[1, 2]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302] 
Functional Description
  
Sequence Annotation
 MOD_RES 15 15 Phosphoserine.
 MOD_RES 17 17 Phosphoserine.
 MOD_RES 24 24 Phosphoserine (By similarity).
 MOD_RES 147 147 Phosphotyrosine.
 MOD_RES 253 253 Phosphothreonine.
 MOD_RES 261 261 Phosphoserine.  
Keyword
 Complete proteome; Phosphoprotein; Polymorphism; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 289 AA 
Protein Sequence
MPVVRKIFRR RRGDSESEED EQDSEEVRLK LEETREVQNL RKRPNGVSAV ALLVGEKVQE 60
ETTLVDDPFQ MKTGGMVDMK KLKERGKDKI SEEEDLHLGT SFSAETNRRD EDADMMKYIE 120
TELKKRKGIV EHEEQKVKPK NAEDCLYELP ENIRVSSAKK TEEMLSNQML SGIPEVDLGI 180
DAKIKNIIST EDAKARLLAE QQNKKKDSET SFVPTNMAVN YVQHNRFYHE ELNAPIRRNK 240
EEPKARPLRV GDTEKPEPER SPPNRKRPAN EKATDDYHYE KFKKMNRRY 289 
Gene Ontology
 GO:0005737; C:cytoplasm; IDA:HPA.
 GO:0005634; C:nucleus; IDA:HPA. 
Interpro
 IPR010756; Hep_59. 
Pfam
 PF07052; Hep_59 
SMART
  
PROSITE
  
PRINTS