CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-041651
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 ATP-binding cassette sub-family A member 2 
Protein Synonyms/Alias
  
Gene Name
 Abca2 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
1336ENSEADVKESRKDALubiquitination[1]
1340ADVKESRKDALPGAEubiquitination[1]
2026QRLPVSTKPVEDDVDubiquitination[1]
Reference
 [1] Synaptic protein ubiquitination in rat brain revealed by antibody-based ubiquitome analysis.
 Na CH, Jones DR, Yang Y, Wang X, Xu Y, Peng J.
 J Proteome Res. 2012 Sep 7;11(9):4722-32. [PMID: 22871113
Functional Description
  
Sequence Annotation
  
Keyword
 ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 2434 AA 
Protein Sequence
MGFLHQLQLL LWKNVTLKRR SPWVLAFEIF IPLVLFFILL GLRQKKPTIS VKEAFYTAAP 60
LTSAGILPVM QSLCPDGQRD EFGFLQYANS TVTQLLERLN RVVEESNLFD PERPSLGSEL 120
EALHQRLEAL SSGPGTWESH SARPAVSSFS LDSVARDKRE LWRFLMQNLS LPNSTAQALL 180
AARVDPSEVY RLLFGPLPDL DGKLGFLRKQ EPWSHLGSNP LFQMEELLLA PALLEQLTCA 240
PGSGELGRIL TMPEGHQVDL QGYRDAVCSG QATARAQHFS DLATELRNQL DIAKIAQQLG 300
FNVPNGSDPQ PQAPSPQSLQ ALLGDLLDVQ KVLQDVDVLS ALALLLPQGA CAGRAPAPQA 360
GSPSGPANST GVGANTGPNT TVEEGTQSPV TPASPDTLQG QCSAFVQLWA GLQPILCGNN 420
RTIEPEALRR GNMSSLGFTS KEQRNLGLLV HLMTSNPKIL YAPAGSEADH VILKANETFA 480
FVGNVTHYAQ VWLNISAEIR SFLEQGRLQQ HLHWLQQYVA DLRLHPEAMN LSLDELPPAL 540
RLDYFSLPNG TALLQQLDTI DNAACGWIQF MSKVSVDIFK GFPDEESIVN YTLNQAYQDN 600
VTVFASVIFQ TRKDGSLPPH VHYKIRQNSS FTEKTNEIRR AYWRPGPNTG GRFYFLYGFV 660
WIQDMIERAI INTFVGHDVV EPGNYVQMFP YPCYTRDDFL FVIEHMMPLC MVISWVYSVA 720
MTIQHIVAEK EHRLKEVMKT MGLNNAVHWV AWFITGFVQL SISVTALTAI LKYGQVLMHS 780
HVLIIWLFLA VYAVATIMFC FLVSVLYSKA KLASACGGII YFLSYVPYMY VAIREEVAHD 840
KITAFEKCIA SLMSTTAFGL GSKYFALYEV AGVGIQWHTF SQSPVEGDDF NLLLAVTMLM 900
VDTVVYGVLT WYIEAVHPGM YGLPRPWYFP LQKSYWLGSG RTETWEWSWP WAHAPRLSVM 960
EEDQACAMES RHFEETRGME EEPTHLPLVV CVDKLTKVYK NDKKLALNKL SLNLYENQVV 1020
SFLGHNGAGK TTTMSILTGL FPPTSGSATI YGHDIRTEMD EIRKNLGMCP QHNVLFDQLT 1080
VEEHLWFYSR LKSMAQEEIR KEMDKMIEDL ELSNKRHSLV QTLSGGMKRK LSVAIAFVGG 1140
SRAIILDEPT AGVDPYARRA IWDLILKYKP GRTILLSTHH MDEADLLGDR IAIISHGKLK 1200
CCGSPLFLKG AYGDGYRLTL VKRPAEPGTS QEPGMASSPS GRPQLSNCSE MQVSQFIRKH 1260
VASSLLVSDT STELSYILPS EAVKKGAFER LFQQLEHSLD ALHLSSFGLM DTTLEEVFLK 1320
VSEEDQSLEN SEADVKESRK DALPGAEGLT AVESQAGNLA RCSELAQSQA SLQSASSVGS 1380
ARGDEGAGYT DGYGDYRPLF DNLQDPDSVS LQEAEMEALA RVGEGSRKLE GWWLKMRQFH 1440
GLLVKRFHCA RRNSKALCSQ ILLPAFFVCV AMTVALSVPE IGDLPPLVLS PSQYHNYTQP 1500
RGNFIPYANE ERREYRLRLS PDASPQQLVS TFRLPSGVGA TCVLKSPANG SLGPMLNLSS 1560
GESRLLAARF FDSMCLESFT QGLPLSNFVP PPPSPAPSDS PLSPDEDSLL AWNTSLPPTA 1620
GPETWTWAPS LPRLVHEPVR CTCSAQGTGF SCPSSVGGHP PQMRVVTGDI LTDITGHNVS 1680
EYLLFTSDRF RLHRYGAITF GNIQKSIPAP IGTRTPLMVR KIAVRRVAQV LYNNKGYHSM 1740
PTYLNSLNNA ILRANLPKSK GNPAAYGITV TNHPMNKTSA SLSLDYLLQG TDVVIAIFII 1800
VAMSFVPASF VVFLVAEKST KAKHLQFVSG CNPVIYWLAN YVWDMLNYLV PATCCIIILF 1860
VFDLPAYTSP TNFPAVLSLF LLYGWSITPI MYPASFWFEV PSSAYVFLIV INLFIGITAT 1920
VATFLLQLFE HDKDLKVVNS YLKSCFLIFP NYNLGHGLME MAYNEYINEY YAKIGQFDKM 1980
KSPFEWDIVT RGLVAMTVEG FVGFFLTIMC QYNFLRQPQR LPVSTKPVED DVDVASERQR 2040
VLRGDADNDM VKIENLTKVY KSRKIGRILA VDRLCLGVRP GECFGLLGVN GAGKTSTFKM 2100
LTGDESTTGG EAFVNGHSVL KDLLQVQQSL GYCPQFDALF DELTAREHLQ LYTRLRGIPW 2160
KDEAQVVRWA LEKLELTKCA DKPAGSYSGG NKRKLSTAIA LIGYPAFIFL DEPTTGMDPK 2220
ARRFLWNLIL DLIKTGRSVV LTSHSMEECE AVCTRLAIMV NGRLRCLGSI QHLKNRFGDG 2280
YMITVRTKSS QNVKDVVRFF NRNFPEAMLK ERHHTKVQYQ LKSEHISLAQ VFSKMEHVVG 2340
VLGIEDYSVS QTTLDNVFVN FAKKQSDNVE QQEAEPSTLP SPLGLLSLLR PRPAPTELRA 2400
LVADEPEDLD TEDEGLISFE EERAQLSFNT DTLC 2434 
Gene Ontology
 GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
 GO:0016887; F:ATPase activity; IEA:InterPro.
 GO:0006200; P:ATP catabolic process; IEA:GOC. 
Interpro
 IPR003593; AAA+_ATPase.
 IPR026082; ABC_A.
 IPR003439; ABC_transporter-like.
 IPR017871; ABC_transporter_CS.
 IPR027417; P-loop_NTPase. 
Pfam
 PF00005; ABC_tran 
SMART
 SM00382; AAA 
PROSITE
 PS00211; ABC_TRANSPORTER_1
 PS50893; ABC_TRANSPORTER_2 
PRINTS