CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-029120
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Phosphorylase b kinase regulatory subunit alpha, skeletal muscle isoform 
Protein Synonyms/Alias
  
Gene Name
 PHKA1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
435RRFSTVPKPDVVVQVubiquitination[1]
452LAETEEIKTILKDKGubiquitination[1]
757LLTELYGKVGEIRHWubiquitination[2]
906LHHILSGKEFGVERSubiquitination[2]
Reference
 [1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [2] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1181 AA 
Protein Sequence
MRSRSNSGVR LDGYARLVQQ TILCHQNPVT GLLPASYDQK DAWVRDNVYS ILAVWGLGLA 60
YRKNADRDED KAKAYELEQS VVKLMRGLLH CMIRQVDKVE SFKYSQSTKD SLHAKYNTKT 120
CATVVGDDQW GHLQLDATSV YLLFLAQMTA SGLHIIHSLD EVNFIQNLVF YIEAAYKTAD 180
FGIWERGDKT NQGISELNAS SVGMAKAALE ALDELDLFGV KGGPQSVIHV LADEVQHCQS 240
ILNSLLPRAS TSKEVDASLL SVVSFPAFAV EDSQLVELTK QEIITKLQGR YGCCRFLRDG 300
YKTPKEDPNR LYYEPAELKL FENIECEWPL FWTYFILDGV FSGNAEQVQE YKEALEAVLI 360
KGKNGVPLLP ELYSVPPDRV DEEYQNPHTV DRVPMGKLPH MWGQSLYILG SLMAEGFLAP 420
GEIDPLNRRF STVPKPDVVV QVSILAETEE IKTILKDKGI YVETIAEVYP IRVQPARILS 480
HIYSSLGCNN RMKLSGRPYR HMGVLGTSKL YDIRKTIFTF TPQFIDQQQF YLALDNKMIV 540
EMLRTDLSYL CSRWRMTGQP TITFPISHSM LDEDGTSLNS SILAALRKMQ DGYFGGARVQ 600
TGKLSEFLTT SCCTHLSFMD PGPEGKLYSE DYDDNYDYLE SGNWMNDYDS TSHDVHMYLP 660
TKLFQASRPS FNLLDSPHPR QENQVPSVRV EIHLPRDQSG EVDFKALVLQ LKETSSLQEQ 720
ADILYMLYTM KGPDWNTELY NERSATVREL LTELYGKVGE IRHWGLIRYI SGILRKKVEA 780
LDEACTDLLS HQKHLTVGLP PEPREKTISA PLPYEALTQL IDEASEGDMS ISILTQEIMV 840
YLAMYMRTQP GLFAEMFRLR IGLIIQVMAT ELAHSLRCSA EEATEGLMNL SPSAMKNLLH 900
HILSGKEFGV ERSVRPTDSN VSPAISIHEI GAVGATKTER TGIMQLKSEI KQVEFRRLSI 960
SAESQSNGGH PLGIDLMSPS FMSPGTSMTP SSGSFPSAYD QQSSKDSRQG QWQRRRRLDG 1020
ALNRVPVGFY QKVWKVLQKC HGLSVEGFVL PSSTTREMTP GEIKFSVHVE SVLNRVPQPE 1080
YRQLLVEAIL VLTMLADIEI HSIGSIIAVE KIVHIANDLF LQEQKTLGAD DTMLAKDPAS 1140
GICTLLYDSA PSGRFGTMTY LSKAAATYVQ EFLPHSICAM Q 1181 
Gene Ontology
 GO:0004553; F:hydrolase activity, hydrolyzing O-glycosyl compounds; IEA:InterPro.
 GO:0005977; P:glycogen metabolic process; IEA:InterPro. 
Interpro
 IPR008928; 6-hairpin_glycosidase-like.
 IPR012341; 6hp_glycosidase.
 IPR011613; Glyco_hydro_15.
 IPR008734; PHK_A/B_su. 
Pfam
 PF00723; Glyco_hydro_15 
SMART
  
PROSITE
  
PRINTS