CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-044597
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Transient receptor potential cation channel subfamily V member 2 
Protein Synonyms/Alias
  
Gene Name
 TRPV2 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
234WSIWKLQKAISVLEMubiquitination[1]
Reference
 [1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Ion channel; Ion transport; Membrane; Reference proteome; Transmembrane; Transport. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 334 AA 
Protein Sequence
MLLTGHILIL LGGIYLLVGQ LWYFWRRHVF IWISFIDSYF EILFLFQALL TVVSQVLCFL 60
AIEWYLPLLV SALVLGWLNL LYYTRGFQHT GIYSVMIQKV ILRDLLRFLL IYLVFLFGFA 120
VALVSLSQEA WRPEAPTGPN ATESVQPMEG QEDEGNGAQY RGILEASLEL FKFTIGMGEL 180
AFQEQLHFRG MVLLLLLAYV LLTYILLLNM LIALMSETVN SVATDSWSIW KLQKAISVLE 240
MENGYWWCRK KQRAGVMLTV GTKPDGSPDE RWCFRVEEVN WASWEQTLPT LCEDPSGAGV 300
PRTLENPVLA SPPKEDEDGA SEENYVPVQL LQSN 334 
Gene Ontology
 GO:0044295; C:axonal growth cone; IEA:Compara.
 GO:0044297; C:cell body; IEA:Compara.
 GO:0009986; C:cell surface; IEA:Compara.
 GO:0012505; C:endomembrane system; IEA:Compara.
 GO:0032584; C:growth cone membrane; IEA:Compara.
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0005622; C:intracellular; IEA:Compara.
 GO:0005262; F:calcium channel activity; IEA:Compara.
 GO:0045773; P:positive regulation of axon extension; IEA:Compara.
 GO:0090280; P:positive regulation of calcium ion import; IEA:Compara.
 GO:0009408; P:response to heat; IEA:Compara. 
Interpro
 IPR005821; Ion_trans_dom.
 IPR008347; TRPV1-4_channel.
 IPR024865; TRPV2_channel.
 IPR024862; TRPV_channel. 
Pfam
 PF00520; Ion_trans 
SMART
  
PROSITE
  
PRINTS
 PR01768; TRPVRECEPTOR.