UniProt Accession

 Q99N15_MOUSE; Q99N15 

Genbank Protein ID

 AL672180; BC027517; AF233685; AK077735; AK088685 

Genbank Nucleotide ID

 AAH27517.1; AAK15008.1; BAC36987.1; BAC40505.1 

Protein Name

 17beta-hydroxysteroid dehydrogenase type 10/short chain L-3-hydroxyacyl-CoA dehydrogenase 

Protein Synonyms/Alias

 3-hydroxyacyl-CoA dehydrogenase type-2; Hydroxysteroid (17-beta) dehydrogenase 10 

Gene Name

 Hsd17b10 

Gene Synonyms/Alias

 Hadh2; Hsd17b10/Schad 

Created Date

 July 27, 2013 

Organism

 Mus musculus (Mouse) 

NCBI Taxa ID

 10090 

Lysine Modification

Position	Peptide	Type	References
9	AAAVRSVKGLVAVVT	acetylation	[1]
9	AAAVRSVKGLVAVVT	ubiquitination	[2]
28	GLGLATAKRLVGQGA	acetylation	[1]
52	SEGEAQAKKLGESCI	acetylation	[1]
69	PANVTSEKEIQAALT	acetylation	[1]
79	QAALTLAKEKFGRID	acetylation	[1]
104	AIKTYHQKKNKIHTL	acetylation	[1]
105	IKTYHQKKNKIHTLE	acetylation	[1]
107	TYHQKKNKIHTLEDF	acetylation	[1]
212	LLTTLPEKVRNFLAS	ubiquitination	[2]

Reference

 [1] Calorie restriction and SIRT3 trigger global reprogramming of the mitochondrial protein acetylome.
 Hebert AS, Dittenhafer-Reed KE, Yu W, Bailey DJ, Selen ES, Boersma MD, Carson JJ, Tonelli M, Balloon AJ, Higbee AJ, Westphall MS, Pagliarini DJ, Prolla TA, Assadi-Porter F, Roy S, Denu JM, Coon JJ.
 Mol Cell. 2013 Jan 10;49(1):186-99. [PMID: 23201123]
 [2] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 261 AA 

Protein Sequence

Gene Ontology

 GO:0005783; C:endoplasmic reticulum; IDA:MGI.
 GO:0005743; C:mitochondrial inner membrane; IDA:MGI.
 GO:0003857; F:3-hydroxyacyl-CoA dehydrogenase activity; IEA:Compara.
 GO:0055114; P:oxidation-reduction process; IEA:GOC. 

Interpro

 IPR002198; DH_sc/Rdtase_SDR.
 IPR002347; Glc/ribitol_DH.
 IPR016040; NAD(P)-bd_dom.
 IPR020904; Sc_DH/Rdtase_CS. 

Pfam

 PF00106; adh_short 

SMART

  

PROSITE

 PS00061; ADH_SHORT 

PRINTS

 PR00081; GDHRDH.
 PR00080; SDRFAMILY.